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Other medical problems
If your symptoms do not improve within a few days, or if they become worse, check with your doctor.

The areas affected by herpes, chickenpox, or shingles should be kept as clean and dry as po ssible. Also, wear loose-fitting clothing to avoid irritating the sores (blisters).

It is important to remember that acyclovir will not keep you from spreading herpes to others.

Possible food and drug interactions when taking this medication
Inform your doctor if you are taking any of the following:
- Lithium (e.g., Lithane) or
- Methotrexate or
- Other medicine for infection or
- Penicillamine (e.g., Cuprimine)

What Is It
Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although not specifically included in product labeling, acyclo vir by injection is used in certain patients with the following medical conditions:

Herpes simplex (for prevention of repeated infections) in people with a weak immune system
Herpes zos ter infections of the eye
Shingles (for prevention of repeated infections) in people with a weak immune system

Special warnings about this medication
Category C. Risk to fetus cannot be ruled out. Consider use if benefit outweighs the potential risk. Exposure registry is available: 1-800-722-9292, ext. 58465 (note: this number is no longer used for antiretroviral drugs. See Health Maintenance section for the pregnancy protocols which contain the antiretroviral registry number.)

Proper Use of This Medicine
Acyclovir comes as an ointment for use on the skin and as a tablet, capsule, and liquid to take by mouth. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take acyclovir exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Use this medication as soon as possi ble after symptoms appear.

What side effects may occur?
Oral: (GI side effects reduced if take with meals)
Short-term therapy: nausea/vomiting, diarrhea, headache, dizziness, fatigue, skin rash, edema. inguinal adenopahty, anorexia, leg pain, medicatio n taste, sore throat.
Long-term: nausea/vomiting, diarrhea, headache, vertigo, insomina, irritability, depression, skin rash, acne. accelerated hair loss, arthralgia, fever, palpitations, sore thr oat, muscle cramps, mestrual abnormalities, lyphadenopathy.


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