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Cautions
tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), and vitamins. If you have taken an MAO inhibitor [phenelzine (Nardil) or tranylcypromine (Parnate)] during the past 2 weeks, do not take sumatriptan. If you have taken another medication for migraine headaches such as dihydroergotamine (D.H.E. 45, Migranal), methysergide (Sansert), naratriptan (Amerge), rizatriptan (Maxalt, Maxalt-MLT), or zolmitriptan (Zomig) during the past 24 hours, do not tak e sumatriptan.

How should you take this medication?
Take Imitrex ( Sumatriptan ) tablets exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. Take each dose with a full glass of water. Take one tablet as soon as you notice symptoms of a migraine, or at any time during an attack. If your symptoms go away, but then return, you can take additional doses as needed e very 2 hours, up to a maximum of 300 mg in 24 hours, unless otherwise directed by your doctor. Never take more than this amount. If your symptoms do not improve at all, call your doctor before taking any more doses of Imitrex ( Sumatriptan ). More medication will not further treat symptoms.

Precautions Before Using This Medicine
Children—Studies on this medicine have been done only in patients 18 years of age or older, and there is no specific information comparing use of .Imitrex in children with use in other age groups.

What side effects can this medication cause?
Less common or rare side effects may include:
- incoordination, increased urination, intolerance of noise or light, itching, jaw discomfort, joint problems, muscle cramps, muscle pain or tendern ess, painful menstruation, pressure in chest, rapid and throbbing heartbeat, rash, ringing in the ears, rise or fall in blood pressure (temporary), sensation of lightness, sensitivity to noise or heat , shivering, shortness of breath, sinus inflammation, sinus or nasal discomfort, skin eruptions, skin redness or tenderness, sleep disturbances, smell disturbances, stomach problems, sweating, swellin g, tearing, thirst, tight feeling in head, tightness in chest, tremors, vision changes or loss

Proper Use of This Medicine
Your doctor may direct you to take another medicine to help prevent headaches. It is important that you follow your doctor's directions, even if your headaches continue to occur. Headache-preventing m edicines may take several weeks to start working. Even after they do start working, your headaches may not go away completely. However, your headaches should occur less often, and they should be less severe and easier to relieve. This can reduce the amount of sumatriptan or pain relievers that you need. If you do not notice any improvement after several weeks of headache-preventing treatment, chec k with your doctor.

Overdose
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

Symptoms of Imitrex overdose may include:
- Bluish tinge to the skin, convulsions, dilated pupils, inactivity, lack of coordination, paralysis, redness in the arms and legs, skin changes at the site of injection, slow breathing, sluggishness, tremor