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Nejm -- Acyclovir For The Prevention Of Recurrent Herpes Simplex Virus Eye Disease
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Overdosage
Symptoms of overdose may include sluggishness, change in amount of urine, loss of consciousness ¡K

How should you take this medication?
Begin taking this medication as soon as symptoms appear. Take this medication as directed. Ask your doctor or pharmacist if you have any questions. Try to take the medication at evenly spaced interval s throughout the day and night. This will ensure a constant blood level of the medication and is most effective.

Other Medicines
Tell you doctor if you are taking any of the following:
- Deferoxamine (e.g., Desferal) (with long-term use) or
- Gold salts (medicine for arthritis) or
- Inflammation or pain medicine

What special precautions should I follow?
Other medicines¡XAlthough certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your do or may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are using any other topical prescription or nonprescription (over-the-counter [OTC]) me dicine that is to be applied to the same area of the skin.

Other medical problems¡XTell your doctor if your herpes simplex infection keeps coming back while you are using acyclovir

What should I do if I forget a dose?
If you are using tablets, capsules, or liquid, take the missed dose as soon as you remember it and take any remaining doses for that day at evenly spaced intervals.

If you are using ointment, apply it as soon as you remember and apply further doses at your regular interval (e.g., every 3 hours) until you go to bed.

However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose of either the ointment or oral medication to make up for a missed one.

Special warnings about this medication
Category C. Risk to fetus cannot be ruled out. Consider use if benefit outweighs the potential risk. Exposure registry is available: 1-800-722-9292, ext. 58465 (note: this number is no longer used for antiretroviral drugs. See Health Maintenance section for the pregnancy protocols which contain the antiretroviral registry number.)


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