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Missing Dose
If you miss a dose, take as soon as remembered; do not take if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

How to Use
Genital herpes (initial): 200mg po q 4 hours 5 times/day X 10 days
Genital herpes (recurrent or suppressive therapy): 400mg 2 times/day for up to 12 months, then re-evaluate.
Herpes zoster: 80 0mg 5 times/day X 7-10 days
Sever HZV or complications: 5-10mg/kg IV q 8 hours X 7-10 days. Administer at constant rate over 1 hour.

Overdosage
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include sluggishness, change in amount of urine, loss of consciousness, or se izures.

What Is It
Acyclovir (ay-SYE-kloe-veer) belongs to the family of medicines called antivirals. Antivirals are used to treat infections caused by viruses. Usually they work for only one kind or group of virus infe ctions.

Topical acyclovir is used to treat the symptoms of herpes simplex virus infections of the skin, mucous membranes, and genitals (sex organs). Although topical acyclovir will not cure herpes simplex, it may help relieve the pain and discomfort and may help the sores (if any) heal faster. Topical acyclovir may also be used for other conditions as determined by your doctor.

Acyclovir is available only with your doctor's prescription, in the following dosage forms:

Topical
Cream (Canada)
Ointment (U.S. and Canada)

Other Medicines
Inform your doctor if you are taking any of the following:
- Lithium (e.g., Lithane) or
- Methotrexate or
- Other medicine for infection or
- Penicillamine (e.g., Cuprimine)

What side effects may occur?
Oral: (GI side effects reduced if take with meals)
Short-term therapy: nausea/vomiting, diarrhea, headache, dizziness, fatigue, skin rash, edema. inguinal adenopahty, anorexia, leg pain, medicatio n taste, sore throat.
Long-term: nausea/vomiting, diarrhea, headache, vertigo, insomina, irritability, depression, skin rash, acne. accelerated hair loss, arthralgia, fever, palpitations, sore thr oat, muscle cramps, mestrual abnormalities, lyphadenopathy.


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