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Other Medicines
Remember that this drug should never be combined with the weight-loss drug fenfluramine (Pondimin); very dangerous side effects could result. This drug may also react badly with alcohol. Avoid alcohol ic beverages while you are taking it.

It is especially important that you check with your doctor before combining this drug with the following:

- Drugs that boost serotonin levels, such as the antidepressants Luvox, Paxil, Prozac, and Zoloft
- Drugs classified as MAO inhibitors, including the antidepressants Nardil and Parnate
- Diabetes medications such as insulin and Micronase
- High blood pressure medications such as guanethidine (Ismelin)

Other medical problems
If you stop taking this drug suddenly after you have taken high doses for a long time, you may find you are extremely fatigued or depressed, or that you have trouble sleeping.

If you continua lly take too much of any appetite suppressant it can cause severe skin disorders, a pronounced inability to fall or stay asleep, irritability, hyperactivity, and personality changes.

Even if your blood pressure is only mildly high, be careful taking this drug.

What side effects can this medication cause?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this medicati on.

Side effects may include:
- Changes in sex drive, constipation, diarrhea, dizziness, dry mouth, exaggerated feelings of depression or elation, headache, high blood pressure, hives, i mpotence, inability to fall or stay asleep, increased heart rate, overstimulation, restlessness, stomach or intestinal problems, throbbing heartbeat, tremors, unpleasant taste

Special warnings about this medication
If you have been taking this medicine for a long time or in large doses and you think you may have become mentally or physically dependent on it, check with your doctor.

- Some signs of depe ndence on appetite suppressants are:
- a strong desire or need to continue taking the medicine.
- a need to increase the dose to receive the effects of the medicine.
- withdrawal side e ffects (for example, mental depression, nausea or vomiting, stomach cramps or pain, trembling, unusual tiredness or weakness) when you stop taking the medicine

Symptoms of overdose
Symptoms of Adipex-P overdose may include:
Abdominal cramps, aggressiveness, confusion, diarrhea, exaggerated reflexes, hallucinations, high or low blood pressure, irregular heartbeat, nausea, pa nic states, rapid breathing, restlessness, tremors, vomiting

Fatigue and depression may follow the stimulant effects of this drug.

In cases of fatal poisoning, convulsions and coma u sually precede death.

What Is It
Adipex-P, an appetite suppressant, is prescribed for short-term use (a few weeks) as part of an overall weight reduction program that also includes dieting, exercise, and counseling. The drug is for u se only by excessively overweight individuals who have a condition--such as diabetes, high blood pressure, or high cholesterol--that could lead to serious medical problems.


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