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Before Using This Medicine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For buspirone, the following should be co
nsidered:
Allergies¡XTell your doctor if you have ever had any unusual or allergic reaction to buspirone. Also tell your health care professional if you are allergic to any other substances,
uch as foods, preservatives, or dyes.
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How to Use
The recommended initial dose is 15 mg daily (5 mg 3 times a day). To achieve an optimal therapeutic response, at intervals of 2 to 3 days the dosage may be increased 5 mg per day, as needed. The maxim
um daily dosage should not exceed 60 mg per day. In clinical trials allowing dose titration, divided doses of 20 to 30 mg per day were commonly employed.
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Special Wanring
CNS:
Dizziness, headache, drowsiness, lightheadedness, insomnia, fatigue, nervousness, decreased concentration, excitement, depression, confusion, nightmares/vivid dreams, anger/hostility. Infrequ
ently (<1%) depersonalization, noise intolerance, euphoria/feeling high, dissociative reaction, fear, loss of interest, dysphoria, hallucinations, seizures, suicidal thoughts. Rarely, slurred speech,
claustrophobia, cold intolerance, stupor, psychosis.
Neurologic:
Paresthesia, weakness, incoordination, tremor, numbness. Infrequently, muscle cramps and spasms, rigid/stiff muscles, involu
ntary movements, akathisia, slowed reaction time. Rarely, tingling of limbs, stiff neck, rigidity of jaw, ataxia.
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DRUG ABUSE AND DEPENDENCE :
Although BuSpar does not intensify the effects of alcohol, it is best to avoid alcohol while taking this medication.
If BuSpar is taken with certain other drugs, the effects of either can be
increased, decreased, or altered. It is especially important to check with your doctor before combining BuSpar with the following:
- The blood-thinning drug Coumadin
- Haloperidol (Hal
dol)
- MAO inhibitors (antidepressant drugs such as Nardil and Parnate)
- Trazodone (Desyrel)
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Symptoms of overdose may include:
- upset stomach
- vomiting
- dizziness
- drowsiness
- blurred vision
- upset stomach
- vomiting
- dizziness
- drowsiness
- blurred vision
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Possible food and drug interactions when taking this medication
Concomitant use of MAO inhibitors and buspirone has been reported to cause an increase in blood pressure. Therefore, concomitant use of these medications is not recommended.
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