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Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:
- Cough; fever; skin rash; sneezing; sore throat; swelling of face, fingers, feet, and/or lower legs

Symptoms of overdose
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

Symptoms of Celebrex overdose may include:
Breathing diffic ulties, coma, drowsiness, gastrointestinal bleeding, high blood pressure, kidney failure, nausea, sluggishness, stomach pain, vomiting

How should this medicine be used?
You should continue to take CELEBREX as prescribed even when you are feeling better. CELEBREX can be taken with or without food. CELEBREX capsules come in 2 strengths: 100 mg and 200 mg.

In O steoarthritis, the recommended dose for CELEBREX is 200 mg a day. CELEBREX delivers 24-hour relief from a once-daily dose of 200 mg. Or if preferred, a dose of 100 mg twice a day is available.

In Rheumatoid Arthritis, the recommended dose for CELEBREX is 100 mg to 200 mg, twice a day. CELEBREX provides relief through the day and through the night.

What Is It
Celecoxib ( sellˇVaˇVCOKSˇVib) is used to relieve some symptoms caused by arthritis, such as inflammation, swelling, stiffness, and joint pain. However, this medicine does not cure arthritis and will p you only as long as you continue to take it.

Celecoxib may also be used for the following problems:

Familial adenomatous polyposis (polyps in the intestines);
Moderate or seve re pain, such as after dental or orthopedic procedures;
Pain during menstruation

What special precautions should I follow?
The presence of other medical problems may affect the use of celecoxib. Make sure you tell your doctor if you have any other medical problems, especially:
- Alcohol abuse or
- Bleeding probl ems or
- Stomach ulcer or other stomach or intestinal problems or
- Tobacco use (or recent history of)ˇXThe chance of side effects may be increased
- Anemia or
- Asthma or
- D hydration or
- Fluid retention (swelling of feet or lower legs) or
- Heart disease or
- High blood pressure or
- Kidney disease or
- Liver diseaseˇXCelecoxib may make these co ditions worse

Significant Interactions:
If Celebrex is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Celebrex with the following:

- ACE-inhibitors (a type of blood pressure and heart medication, including such drugs as Capoten, Vasotec, and Prinivil)
- Blood thinning agents such as Coumadin
- Fluco nazole (Diflucan)
- Furosemide (Lasix)
- Lithium (Eskalith, Lithobid)
- Thiazide diuretics (water pills) such as hydrochlorothiazide and Dyazide

If you take low-dose aspirin t o protect against heart attack, you can continue taking it with Celebrex.


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