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Before Using This Medicine
Before taking celecoxib,
- tell your doctor and pharmacist if you are allergic to celecoxib, aspirin or other nonsteroidal anti-inflammatory drugs, sulfas, or any other drugs.
- tell your doc tor if you have or have ever had liver, heart, or kidney disease; high blood pressure; asthma; any stomach problems including ulcers or bleeding; or any other gastrointestinal disease.
- tell you r doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking celecoxib, call your doctor.
- if you are having surgery, including dental surger y, tell the doctor or dentist that you are taking celecoxib

Overdosage
Bloody or black, tarry stools; continuing thirst; dizziness; drowsiness ; headache, severe or continuing; nausea and/or vomiting; shortness of breath; stomach pain; sudden decrease in the amou nt of urine; swelling of face, fingers, and/or lower legs; tightness in chest and/or wheezing; troubled breathing; unusual tiredness or weakness; vomiting of blood or material that looks like cof fee grounds; weight gain
- lack of energy
- drowsiness
- upset stomach
- vomiting
- stomach pain

What side effects may occur?
Although side effects from celecoxib are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:

- water retention
- upset stomach
- sto mach pain or cramps
- diarrhea
- gas
- headache

If you experience any of the following symptoms, call your doctor immediately:

- bloody vomit
- bloody diarrhea or black, tarry stools
- ringing in the ears
- blurred vision
- swelling of the hands, feet, ankles, or lower legs
- skin rash
- itching
- yellowing of the skin or eyes < br> - unexplained weight gain


Significant Interactions:
Include on your medical history/personal profile all of the other medicines you are taking or plan to take while you are on CELEBREX, even other medicines that you can get without a prescription. CELE BREX has significant drug interactions with :

- Methotrexate (a medicine used to suppress the immune system).

- Warfarin (a blood thinner).

- Rifampin (an antibiotic).
< br> - ACE inhibitors (medicines used for high blood pressure and heart failure).

- Lithium (a medicine used to treat a certain type of depression).

What is this Drug
Celebrex is a drug that helps relieve pain associated with osteoarthritis and adult rheumatoid arthritis. The reason that Celebrex has become so popular is because it is easier on the stomach than oth er anti-arthritis medication. Celebrex is used to relieve the pain, tenderness, inflammation (swelling), and stiffness caused by arthritis. This medicine is a nonsteroidal anti-inflammatory drug (NSAI D) known as a COX-2 inhibitor used to relieve the symptoms of osteoarthritis and rheumatoid arthritis in adults. Reporting on the 63rd Annual Meeting of the American College of Rheumatology in Decembe r, thirdage.com reported that in analysis of 800 arthritis patients, more than one-third had stopped taking medications because they couldn't handle the stomach pains associated with the drugs.

How should this medicine be used?
You should continue to take CELEBREX as prescribed even when you are feeling better. CELEBREX can be taken with or without food. CELEBREX capsules come in 2 strengths: 100 mg and 200 mg.

In O steoarthritis, the recommended dose for CELEBREX is 200 mg a day. CELEBREX delivers 24-hour relief from a once-daily dose of 200 mg. Or if preferred, a dose of 100 mg twice a day is available.

In Rheumatoid Arthritis, the recommended dose for CELEBREX is 100 mg to 200 mg, twice a day. CELEBREX provides relief through the day and through the night.


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