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Before Using This Medicine
Strong allergic reactions to Diflucan, although rare, have been reported. Symptoms may include hives, itching, swelling, sudden drop in blood pressure, difficulty breathing or swallowing, diarrhea, or abdominal pain. If you experience any of these symptoms, notify your doctor immediately.

Special warnings about this medication
If you are taking antacids, cimetidine (e.g., Tagamet), famotidine (e.g., Pepcid), nizatidine (e.g., Axid), omeprazole (e.g., Prilosec), or ranitidine (e.g., Zantac) while you are taking itraconazole or ketoconazole, take the other medicine at least 2 hours after you take itraconazole or ketoconazole . If you take these medicines at the same time that you take itraconazole or ketoconazole, they wi ll keep your antifungal medicine from working properly.

What is this medicine
Diflucan are used to treat serious fungus infections that may occur in different parts of the body. These medicines may also be used for other problems as determined by your doctor

How should this medicine be used?
Fluconazole comes as a tablet and liquid to take by mouth. It is usually taken once a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take fluconazole exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the liquid well before each use to mix the medication evenly.

Continue to take fluconazole even if you feel well. Do not stop taking fluconazole without talking to your doctor.

Side Effects of This Medicine
Check with your doctor immediately if any of the following side effects occur:

- Dark or amber urine; fever and sore throat; loss of appetite; pale stools; reddening, blistering, peeling, or loosening of skin and mucous membranes; stomach pain; unusual bleeding or bruising; unusual tiredness or weakness; yellow eyes or skin
- Fever and chills; skin rash or itching

Drug Interactions
When you are taking Diflucan, it is especially important that your health care professional know if you are taking any of the following:

- Terfenadine (e.g., Seldane)¡XThese medicines should not be taken with fluconazole, itraconazole, or ketoconazole; these Diflucan may increase the chance of serious side effects of astemizole or terfenadine
- Atorvastatin (e.g., Lipitor) or
- Cerivastatin (e.g., Baycol) or
- Lovastatin (e.g., Mevacor) or
- Simvastatin (e.g., Zocor)¡XUse of these drugs with itraconazole or ketoconazole since increased levels of these drugs can cau e serious muscular disorders.
- Busulfan (e.g., Myleran) or
- Docetaxel (e.g., Taxotere) or
- Vinblastine (e.g., Velban) or


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