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What side effects may occur?
Although side effects from fluconazole are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:

- upset stomach
- loss of appetite
- altered taste
- diarrhea or loose stools
- headache
- dizziness
- fatigue

If you experience any of the following symptoms, call your doctor immediately:

- rash
- itching
- vomiting
- yellowing of the skin or eyes
- dark urine
- pale stools

What is this medicine
Fluconazole is used to treat pneumonia, meningitis, and fungal infections of the mouth, throat, liver, kidneys, heart, urinary tract, and abdomen. It also has been used to treat vaginal infections and oral thrush in certain patients.

Proper Use of This Medicine
You can take Diflucan with or without meals.

Take this medication exactly as prescribed, and continue taking it for as long as your doctor instructs. You may begin to feel better after the f irst few days; but it takes weeks or even months of treatment to completely cure certain fungal infections

Precautions Before Using This Medicine
The effects of Diflucan during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Diflucan appears in breast milk and could aff ect a nursing infant. If this medication is essential to your health, your doctor may advise you to stop breastfeeding until your treatment with Diflucan is finished.

Precautions while Using this Medicine
If you are taking antacids, cimetidine (e.g., Tagamet), famotidine (e.g., Pepcid), nizatidine (e.g., Axid), omeprazole (e.g., Prilosec), or ranitidine (e.g., Zantac) while you are taking itraconazole or ketoconazole, take the other medicine at least 2 hours after you take itraconazole or ketoconazole . If you take these medicines at the same time that you take itraconazole or ketoconazole, they wi ll keep your antifungal medicine from working properly.

Significant Interactions:
If Diflucan is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Diflucan with the following:

- Blood-thinning drugs such as Coumadin
- Antidiabetic drugs such as Orinase, DiaBeta, and Glucotrol
- Astemizole (Hismanal)
- Cisapride (Propulsid)
- Cyclospo rine (Sandimmune, Neoral)
- Hydrochlorothiazide (HydroDIURIL)
- Phenytoin (Dilantin)
- Rifabutin (Mycobutin)
- Rifampin (Rifadin)
- Tacrolimus (Prograf)
- Terfenadine (Se ldane)
- Theophylline (Theo-Dur)
- Ulcer medications such as Tagamet


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