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Other Medicines
It is especially important that your health care professional know if you are taking any of the following:
- Antidepressants, tricyclic (amitriptyline [e.g., Elavil], amoxapine [e.g., Asendi
n], clomipramine [e.g., Anafranil], desipramine [e.g., Pertofrane], doxepin [e.g., Sinequan], imipramine [e.g., Tofranil], nortriptyline [e.g., Aventyl], protriptyline [e.g., Vivactil], trimipramine [
e.g., Surmontil]) or
- Central nervous system (CNS) depressants (medicines that often cause drowsiness)ˇXThese medicines may add to the effects of butalbital and increase the chance of drowsiness
or other side effects
- Divalproex (e.g., Depakote) or
- Valproic acid (e.g., Depakene)ˇXThe chance of side effects may be increased
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How to Use
People who get a lot of headaches may need to take a different medicine to help prevent headaches. It is important that you follow your doctor's directions about taking the other medicine, even if you
r headaches continue to occur. Headache-preventing medicines may take several weeks to start working. Even after they do start working, your headaches may not go away completely. However, your headach
es should occur less often, and they should be less severe and easier to relieve than before. This will reduce the amount of headache relievers that you need. If you do not notice any improvement afte
r several weeks of headache-preventing treatment, check with your doctor.
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Why is this medication prescribed?
Butalbital and acetaminophen (byoo-TAL-bi-tal and a-seat-a-MIN-oh-fen) combination is a pain reliever and relaxant. It is used to treat tension headaches. Butalbital belongs to the group of medicines
called barbiturates (bar-BI-tyoo-rates) . Barbiturates act in the central nervous system (CNS) to produce their effects.
When you take butalbital for a long time, your body may get used to i
t so that larger amounts are needed to produce the same effects. This is called tolerance to the medicine. Also, butalbital may become habit-forming (causing mental or physical dependence) when it is
used for a long time or in large doses. Physical dependence may lead to withdrawal side effects when you stop taking the medicine.
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Special warnings about this medication
Before having any kind of surgery (including dental surgery) or emergency treatment, tell the medical doctor or dentist in charge that you are taking this medicine. Serious side effects can occur if y
our medical doctor or dentist gives you certain medicines without knowing that you have taken butalbital.
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Missed Dose
Take the missed dose as soon as you remember. Do not takedouble dose of Esgic . Wait the prescribed amount of time before taking your next dose.
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What side effects may occur?
Check with your doctor immediately if any of the following side effects occur, especially if several of them occur together:
Bleeding or crusting sores on lips; chest pain; fever with or wi
thout chills; hive-like swellings (large) on eyelids, face, lips, and/or tongue ; muscle cramps or pain; red, thickened, or scaly skin; shortness of breath, troubled breathing, tightness in chest,
or wheezing; skin rash, itching, or hives; sores, ulcers, or white spots in mouth (painful); sore throat
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