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How should this medicine be used?
Take acetaminophen / butalbital / caffeine - Fioricet exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. Take
each dose with a full glass of water. Take acetaminophen / butalbital / caffeine with food or milk if it upsets your stomach. Never take more acetaminophen / butalbital / caffeine than is prescribed f
or you. If your pain is not being adequately treated, talk to your doctor. Store acetaminophen / butalbital / caffeine at room temperature away from moisture and heat.
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Special warnings about this medication
Check the labels of all nonprescription (over-the-counter [OTC]) or prescription medicines you now take. If any contain a barbiturate or acetaminophen, check with your health care professional. Taking
them together with this medicine may cause an overdose.
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Before Using This Medicine
Before taking acetaminophen, butalbital, and caffeine,
tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially anticoagulants ('blood thin
ners') such as warfarin (Coumadin), antidepressants, antihistamines, pain medications, sedatives, sleeping pills, tranquilizers, and vitamins. Many nonprescription pain relievers contain acetaminophen
. Too much of this drug can be harmful.
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Possible Side Effect
If you experience any of the following serious side effects, stop taking acetaminophen / butalbital / caffeine - Fioricet and seek emergency medical attention: an allergic reaction (difficulty breathi
ng; closing of your throat; swelling of your lips, tongue, or face; or hives); slow, weak breathing; liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleedin
g or bruising, severe fatigue); blood problems (easy or unusual bleeding or bruising); or low blood sugar (fatigue, increased hunger or thirst,
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Overdosage
Symptoms of Fioricet overdose can be due to its barbiturate or its acetaminophen component.
Symptoms of barbiturate poisoning may include:
- Coma, confusion, drowsiness, low blood press
ure, shock, slow or troubled breathing
Overdose due to the acetaminophen component of Fioricet may cause kidney and liver damage, blood disorders, or coma due to low blood sugar. Massive dos
es may cause liver failure.
Symptoms of liver damage include:
- Excess perspiration, feeling of bodily discomfort, nausea, vomiting
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Drug Interactions
Butalbital slows the central nervous system (CNS) and intensifies the effects of alcohol and other CNS depressants. Use of alcohol with this drug may also cause overdose symptoms. Avoid alcoholic beve
rages while taking Fioricet.
It is especially important to check with your doctor before combining Fioricet with the following:
- Antihistamines such as Benadryl
- Drugs known
as monoamine oxidase inhibitors, including the antidepressants Nardil and Parnate
- Drugs to treat depression such as Elavil
- Major tranquilizers such as Haldol and Thorazine
- Muscle
relaxants such as Flexeril
- Narcotic pain relievers such as Darvon
- Sleep aids such as Halcion
- Tranquilizers such as Xanax and Valium
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