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Proper Use of This Medicine
Do not use .Imitrex for a headache that is different from your usual migraines . Instead, check with your doctor.

To relieve your migraine as soon as possible, use .Imitrex as soon as the hea dache pain begins. Even if you get warning signals of a coming migraine (an aura), you should wait until the headache pain starts before using .Imitrex. Using .Imitrex during the aura probably will no t prevent the headache from occurring. However, even if you do not use .Imitrex until your migraine has been present for several hours, the medicine will still work.

Lying down in a quiet, da rk room for a while after you use this medicine may help relieve your migraine.

Other Medicines
If Imitrex is taken with certain other drugs, the effects of either may be increased, decreased, or altered. It is important to check with your doctor before combining Imitrex with the following:

- Drugs classified as MAO inhibitors, including the antidepressants Nardil and Parnate
- Ergot-containing drugs such as Cafergot and Ergostat
- Fluoxetine (Prozac)
- Fluvoxamine ( Luvox)
- Paroxetine (Paxil)
- Sertraline (Zoloft)

Overdosage
Seek emergency medical attention. Symptoms of a Imitrex ( Sumatriptan ) overdose might include tremor, redness, or a warm feeling in your arms and legs, irregular breathing, large pupils; an uncoordin ated feeling; and chest pain.

What side effects may occur?
If you experience any of the following serious side effects, stop taking Imitrex ( Sumatriptan ) and seek emergency medical attention: an allergic reaction (difficulty breathing; closing of your throa t; swelling of your lips, tongue, or face; or hives); or severe or prolonged chest pain or an irregular heartbeat. Other, less serious side effects may be more likely to occur. Continue to take Imitre x ( Sumatriptan ) and talk to your doctor if you experience nausea; drowsiness

Special warnings about this medication
tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), and vitamins. If you have taken an MAO inhibitor [phenelzine (Nardil) or tranylcypromine (Parnate)] during the past 2 weeks, do not take sumatriptan. If you have taken another medication for migraine headaches such as dihydroergotamine (D.H.E. 45, Migranal), methysergide (Sansert), naratriptan (Amerge), rizatriptan (Maxalt, Maxalt-MLT), or zolmitriptan (Zomig) during the past 24 hours, do not tak e sumatriptan.

Other medical problems
PregnancyˇX.Imitrex has not been studied in pregnant women. However, in some animal studies, .Imitrex caused harmful effects to the fetus. These unwanted effects usually occurred when .Imitrex was giv n in amounts that were large enough to cause harmful effects in the mother.


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