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Proper Use of This Medicine
If you are not much better in 1 or 2 hours after an injection of sumatriptan, or in 2 to 4 hours after a tablet is taken, do not use any more of this medicine for the same migraine. A migraine that is not relieved by the first dose of sumatriptan probably will not be relieved by a second dose, either. Ask your doctor ahead of time about other medicine to be taken if sumatriptan does not work. Afte r taking the other medicine, check with your doctor as soon as possible. Headaches that are not relieved by sumatriptan are sometimes caused by conditions that need other treatment. However, even if s umatriptan does not relieve one migraine, it may still relieve the next one.

Other Medicines
Tell your health care professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine, especially other prescription medicine for migraine headaches, or if y ou smoke tobacco.

When you are taking .Imitrex, it is especially important that your health care professional know if you are taking the following:

Monoamine oxidase (MAO) inhibitor activity (isocarboxazid [e.g., Marplan], phenelzine [e.g., Nardil], procarbazine [e.g., Matulane], selegiline [e.g., Eldepryl], tranylcypromine [e.g., Parnate])¡XTaking .Imitrex while you are taking r within 2 weeks of taking MAO inhibitors may cause sudden high body temperature, extremely high blood pressure and severe convulsions;

Cautions
Check with your doctor if you have used .Imitrex for three headaches, and have not had good relief. Also, check with your doctor if your migraine headaches are worse, or if they are occurring more oft en, than before you started using .Imitrex.

Drinking alcoholic beverages can make headaches worse or cause new headaches to occur. People who suffer from severe headaches should probably avoi d alcoholic beverages, especially during a headache.

Some people feel drowsy or dizzy during or after a migraine, or after taking .Imitrex to relieve a migraine. As long as you are feeling dr owsy or dizzy, do not drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert.

How to Use
.Imitrex comes as a tablet to take by mouth and a nasal spray. It should be used at the first sign of a migraine headache. If you are at risk for heart disease and you have never taken .Imitrex before , you may need to take the first dose in your doctor's office. Usually only one dose is needed. If pain is not relieved with the first dose, your doctor may prescribe a second dose to be taken after a t least 2 hours. Do not take more than 200mg of the tablets or 40 mg of the nasal spray in any 24-hour period. Follow the directions on your prescription label carefully, and ask your doctor or pharma cist to explain any part you do not understand. Take .Imitrex exactly as directed.

Side Effects of This Medicine
More common side effects may include:
Burning sensation, dizziness or vertigo, feeling of heaviness, feeling of tightness, flushing, mouth and tongue discomfort, muscle weakness, nausea (nasal sp ray), neck pain and stiffness, numbness, pressure sensation, redness at the site of injection, sinus or nasal discomfort (nasal spray), sore throat, tingling, unusual taste (nasal spray), vomiting (na sal spray), warm/cold sensation

Precautions Before Using This Medicine
Allergies¡XTell your doctor if you have ever had any unusual or allergic reaction to .Imitrex. Also tell your health care professional if you are allergic to any other substances, such as foods, prese vatives, or dyes.


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