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Other medical problems
The presence of other medical problems may affect the use of .Imitrex. Make sure you tell your doctor if you have any other medical problems, especially:
- Angina (chest pain) or
- Fast or i rregular heartbeat or
- Heart or blood vessel disease or
- High blood pressure or
- Kidney disease or
- Liver disease or
- Stroke (history of)¡XThe chance of side effects may e increased. Heart or blood vessel disease and high blood pressure sometimes do not cause any symptoms, so some people do not know that they have these problems. Before deciding whether you should use .Imitrex, your doctor may need to do some tests to make sure that you do not have any of these conditions.

Side Effects
If your headache does not feel like any you have been experiencing, do not take Imitrex.

Use Imitrex cautiously if you have liver or kidney disease. Also, if you have any trouble with your e yes, tell your doctor.

Imitrex is not recommended for adults over 65. It has not been tested in children.

Although very rare, severe and even fatal allergic reactions have occurred in people taking Imitrex. Such reactions are more likely in people who have several allergies. In rare cases, people have suffered seizures after taking Imitrex.

Cautions
tell your doctor if you smoke, if you have a strong family history of heart disease, if you are postmenopausal, or if you are a man over 40. Also tell your doctor if you have or have ever had high blo od pressure; angina (recurring chest pain); a heart attack; diabetes; high cholesterol; obesity; stroke; transient ischemic attack (mini-stroke); ischemic bowel disease; coronary artery disease; seizu res; or blood vessel, kidney, or liver disease.

Proper Use of This Medicine
Your doctor may direct you to take another medicine to help prevent headaches. It is important that you follow your doctor's directions, even if your headaches continue to occur. Headache-preventing m edicines may take several weeks to start working. Even after they do start working, your headaches may not go away completely. However, your headaches should occur less often, and they should be less severe and easier to relieve. This can reduce the amount of sumatriptan or pain relievers that you need. If you do not notice any improvement after several weeks of headache-preventing treatment, chec k with your doctor.

Overdose
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

Symptoms of Imitrex overdose may include:
- Bluish tinge to the skin, convulsions, dilated pupils, inactivity, lack of coordination, paralysis, redness in the arms and legs, skin changes at the site of injection, slow breathing, sluggishness, tremor

Drug Interactions
Do not take Imitrex ( Sumatriptan ) if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) within the last 14 days. T he combination could cause seizures, nausea, vomiting, sweating, flushing,


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