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Significant Interactions:
Tell your health care professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine, especially other prescription medicine for migraine headaches, or if y
ou smoke tobacco.
When you are taking .Imitrex, it is especially important that your health care professional know if you are taking the following:
Monoamine oxidase (MAO) inhibitor
activity (isocarboxazid [e.g., Marplan], phenelzine [e.g., Nardil], procarbazine [e.g., Matulane], selegiline [e.g., Eldepryl], tranylcypromine [e.g., Parnate])¡XTaking .Imitrex while you are taking
r within 2 weeks of taking MAO inhibitors may cause sudden high body temperature, extremely high blood pressure and severe convulsions;
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How to Use
If you feel much better after a dose of sumatriptan, but your headache comes back or gets worse after a while, you may use more sumatriptan. However, use this medicine only as directed by your doctor.
Do not use more of it, and do not use it more often, than directed. Using too much sumatriptan may increase the chance of side effects.
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What special precautions should I follow?
tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft),
and vitamins. If you have taken an MAO inhibitor [phenelzine (Nardil) or tranylcypromine (Parnate)] during the past 2 weeks, do not take sumatriptan. If you have taken another medication for migraine
headaches such as dihydroergotamine (D.H.E. 45, Migranal), methysergide (Sansert), naratriptan (Amerge), rizatriptan (Maxalt, Maxalt-MLT), or zolmitriptan (Zomig) during the past 24 hours, do not tak
e sumatriptan.
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How should you take this medication?
Imitrex tablets should be swallowed whole, with liquid. If you have had no relief 2 hours after taking Imitrex Tablets, you may take a second dose of up to 100 milligrams, if your doctor advises it. I
f the headache returns, you may take additional doses at intervals of at least 2 hours. You should not take more than 300 milligrams in one day. If your headache returns after you have had an Imitrex
Injection, you may take single Imitrex Tablets, at intervals of at least 2 hours, up to a maximum of 200 milligrams in a day.
Imitrex nasal spray is packaged in single-dose bottles containin
g either 5 or 20 milligrams of the drug. The usual dosage is a single spray in one nostril.
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Before Using This Medicine
Children¡XStudies on this medicine have been done only in patients 18 years of age or older, and there is no specific information comparing use of .Imitrex in children with use in other age groups.
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Side Effects of This Medicine
Less common or rare side effects may include:
- Abdominal discomfort, agitation, allergic reactions (severe), anxiety, asthma, backache, backflow of stomach contents, bleeding between periods, bl
eeding in ears, nose or throat, breast tenderness, burning/numbness of tongue, changes in heart rhythm, chills, cold sensation, confusion, constipation, cough, depression, diarrhea, difficult or labor
ed breathing, difficult or painful urination, difficulty concentrating, difficulty speaking, difficulty swallowing, drowsiness/calmness, dry mouth, ear infection, ear pain, exaggerated feeling of well
-being, eye irritation, facial pain, fainting, fatigue, feeling strange, fever, general feeling of illness, headache, hearing loss, hearing disturbance,
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