is when you should be well on your way to a new lifestyle and ready to stop MERIDIA.

Appetite suppressants are not a substitute for proper diet. For maximum effects, this must be used in conjunction with a diet and exercise progra m.

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Other medical problems
Breast-feeding—It is not known whether Meridia passes into breast milk. Although most medicines pass into breast milk in small amounts, many of them may be used safely while breast-feeding. A mother w ho is taking this medicine and who wishes to breast-feed should discuss this with her doctor.

What Is It
Patients treated with MERIDIA while on a reduced calorie diet showed significant weight loss during the first 6 months of treatment, and significant weight loss was maintained for one year. In one 12- month study, the average weight loss in patients taking MERIDIA, 10 mg daily, was about 10 lbs. and in those taking 15 mg daily was about 14 lbs. The average weight loss in persons on only a reduced c alorie diet alone was 3 1/2 lbs. Thus, MERIDIA is proven effective therapy for the obese patient who needs to loose weight to decease morbidity. Nonetheless, the magnitude of the weight loss will ulti mately depend on the degree of concomitant caloric restriction and the concomitant use of a graded exercise program.

How should you take this medication?
Meridia comes as a capsule to take by mouth. It is usually taken once a day and may be taken with or without food. Follow the directions on your prescription label carefully, and ask your doctor or ph armacist to explain any part you do not understand.

Take Meridia exactly as directed. Meridia can be habit forming. Do not take a larger dose, take it more often, or for a longer period than your doctor tells you to.

Precautions while Using this Medicine
Meridia may cause dizziness, drowsiness, or poor judgment. Be sure you know how you react to this medicine before you drive, operate machinery, or do other things that could be dangerous if you are no t alert and able to think clearly.

Meridia may cause dryness of the mouth. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. Howeve r, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth deca y, gum disease, and fungus infections.

MERIDIA is a short-term drug that helps you to start losing weight and then keep on going when you are ready to carry on, on your own. Your body starts to build up a resistance to the effects of MERIDIA after a few weeks of treatment, which
When you are taking Meridia, it is especially important that your health care professional know if you are taking any of the following:

- Appetite suppressants, other (benzphetamine [e.g., D idrex], diethylpropion [e.g., Tenuate], mazindol [e.g., Sanorex], phendimetrazine [e.g., Phendiet], phentermine [e.g., Ionamin])—The effects of using Meridia in combination with another appetite suppr essant are not known
- Bromocriptine (e.g., Parlodel) or
- Buspirone (e.g., BuSpar) or
- Certain tricyclic antidepressants (amitriptyline [e.g., Elavil], clomipramine [e.g., Anafranil], imipramine [e.g., Tofranil]) or
- Dextromethorphan (cough medicine) or
- Levodopa (e.g., Sinemet) or
- Lithium (e.g., Eskalith)

Possible Side Effect
If you experience any of the following symptoms, call your doctor immediately:

- excessive sweating
- dilated pupils
- fast or irregular heartbeat
- vomiting
- extreme ex citement
- restlessness
- anxiety
- dizziness
- confusion
- loss of consciousness
- uncoordinated or abnormal movement
- flushing (feeling of warmth)
- difficul t speech
- eye pain
- tremor
- seizures
- chest pain
- excessive bruising or unusual bleeding
- rash
- hives