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is when you should be well on your way to a new lifestyle and ready to stop MERIDIA.

Appetite suppressants are not a substitute for proper diet. For maximum effects, this must be used in conjunction with a diet and exercise progra m.


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MERIDIA is a short-term drug that helps you to start losing weight and then keep on going when you are ready to carry on, on your own. Your body starts to build up a resistance to the effects of MERIDIA after a few weeks of treatment, which
When you are taking Meridia, it is especially important that your health care professional know if you are taking any of the following:

- Tramadol (e.g., Ultram) or
- Trazodone (e.g., D esyrel) or
- Tryptophan or
- Venlafaxine (e.g., Effexor)¡XUsing these medicines with Meridia may increase the chance of developing a rare, but very serious, unwanted effect known as the serot onin syndrome. Symptoms of this syndrome include confusion, diarrhea, fever, poor coordination, restlessness, shivering, sweating, talking or acting with excitement you cannot control, trembling or sh aking, or twitching. If you develop these symptoms, contact your doctor as soon as possible

What Is It
Patients treated with MERIDIA while on a reduced calorie diet showed significant weight loss during the first 6 months of treatment, and significant weight loss was maintained for one year. In one 12- month study, the average weight loss in patients taking MERIDIA, 10 mg daily, was about 10 lbs. and in those taking 15 mg daily was about 14 lbs. The average weight loss in persons on only a reduced c alorie diet alone was 3 1/2 lbs. Thus, MERIDIA is proven effective therapy for the obese patient who needs to loose weight to decease morbidity. Nonetheless, the magnitude of the weight loss will ulti mately depend on the degree of concomitant caloric restriction and the concomitant use of a graded exercise program.

How should this medicine be used?
Meridia comes as a capsule to take by mouth. It is usually taken once a day and may be taken with or without food. Follow the directions on your prescription label carefully, and ask your doctor or ph armacist to explain any part you do not understand.

Take Meridia exactly as directed. Meridia can be habit forming. Do not take a larger dose, take it more often, or for a longer period than your doctor tells you to.

Special warnings about this medication
Meridia may cause dizziness, drowsiness, or poor judgment. Be sure you know how you react to this medicine before you drive, operate machinery, or do other things that could be dangerous if you are no t alert and able to think clearly.

Meridia may cause dryness of the mouth. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. Howeve r, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth deca y, gum disease, and fungus infections.

What side effects may occur?
Although side effects from Meridia are not common, they can occur. Tell you doctor if any of these symptoms are severe or do not go away:

- headache
- constipation
- back pain
- insomnia
- dry mouth
- nervousness
- changes in mood
- upset stomach
- stomach pain
- gas
- changes in taste
- increased appetite
- loss of appetite
- runny nose
- flu-like symptoms
- irregular or painful menstrual periods
- swelling of the hands, feet, ankles, or lower legs




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