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is when you should be well on your way to a new lifestyle and ready to stop MERIDIA.

Appetite suppressants are not a substitute for proper diet. For maximum effects, this must be used in conjunction with a diet and exercise progra m.


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MERIDIA is a short-term drug that helps you to start losing weight and then keep on going when you are ready to carry on, on your own. Your body starts to build up a resistance to the effects of MERIDIA after a few weeks of treatment, which
When you are taking Meridia, it is especially important that your health care professional know if you are taking any of the following:

- Appetite suppressants, other (benzphetamine [e.g., D idrex], diethylpropion [e.g., Tenuate], mazindol [e.g., Sanorex], phendimetrazine [e.g., Phendiet], phentermine [e.g., Ionamin])¡XThe effects of using Meridia in combination with another appetite suppr essant are not known
- Bromocriptine (e.g., Parlodel) or
- Buspirone (e.g., BuSpar) or
- Certain tricyclic antidepressants (amitriptyline [e.g., Elavil], clomipramine [e.g., Anafranil], imipramine [e.g., Tofranil]) or
- Dextromethorphan (cough medicine) or
- Levodopa (e.g., Sinemet) or
- Lithium (e.g., Eskalith)

What Is It
Meridia (si-BYOO-tra-meen) is used together with a reduced-calorie diet to help you lose weight and to help keep the lost weight from returning. Meridia is thought to work by increasing the activity o f certain chemicals, called norepinephrine and serotonin, in the brain. This medicine is approved for use only in people who are very overweight.

Side Effects
If you have narrow-angle glaucoma or thyroid problems, make sure the doctor knows; Meridia should be used with caution in these circumstances. If you are prone to gallstones, be aware that weight loss can cause more of them to form. Meridia has not been tested in people under 16 years old. It should be used with caution in those over 65. Although it has been classified as a controlled substance (p otentially subject to abuse), the possibility of developing physical or psychological dependence is low.

How to Use
Meridia comes as a capsule to take by mouth. It is usually taken once a day and may be taken with or without food. Follow the directions on your prescription label carefully, and ask your doctor or ph armacist to explain any part you do not understand.

Take Meridia exactly as directed. Meridia can be habit forming. Do not take a larger dose, take it more often, or for a longer period than your doctor tells you to.

Cautions
Do not take Meridia while you are taking or within 2 weeks of taking medicines with monoamine oxidase (MAO) inhibitor activity , such as isocarboxazid (e.g., Marplan), phenelzine (e.g., Nardil), proca rbazine (e.g., Matulane), selegiline (e.g., Eldepryl), or tranylcypromine (e.g., Parnate). Do not take an MAO inhibitor within 2 weeks of taking Meridia. To do so may cause severe seizures, extremely high blood pressure, or a life-threatening adverse effect called the serotonin syndrome.

Precautions Before Using This Medicine
Children¡XStudies on this medicine have been done only in adult patients, and there is no specific information comparing use of Meridia in children with use in other age groups.


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