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Cautions
Meridia may cause dizziness, drowsiness, or poor judgment. Be sure you know how you react to this medicine before you drive, operate machinery, or do other things that could be dangerous if you are no t alert and able to think clearly.

Meridia may cause dryness of the mouth. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. Howeve r, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth deca y, gum disease, and fungus infections.

Side Effects
Check with your doctor as soon as possible if any of the following side effects occur:

- Achiness; chills; fast or irregular heartbeat; increased blood pressure ; mental depression; pain ful menstruation; swelling of body or of feet and ankles

- Bruising or red spots or patches on skin; convulsions (seizures); excessive bleeding following injury; headache (severe); ra pidly changing moods; skin rash; weight gain (unusual)

Before Using This Medicine
The presence of other medical problems may affect the use of Meridia. Make sure you tell your doctor if you have any other medical problems, especially:
- Anorexia nervosa (an eating disorder) or
- Glaucoma, narrow angle or
- High blood pressure (or history of)ˇXMeridia may make these conditions worse
- Brain disease or damage, or mental retardation or
- Seizures (history f)ˇXMeridia may increase the chance of having seizures
- Gallstones (or history of)ˇXWeight loss may make this condition worse
- Heart disease (or history of) or
- Stroke (or history of Increased blood pressure or heart rate caused by Meridia may make these conditions worse
- Kidney disease (severe)

What is this Drug
Patients treated with MERIDIA while on a reduced calorie diet showed significant weight loss during the first 6 months of treatment, and significant weight loss was maintained for one year. In one 12- month study, the average weight loss in patients taking MERIDIA, 10 mg daily, was about 10 lbs. and in those taking 15 mg daily was about 14 lbs. The average weight loss in persons on only a reduced c alorie diet alone was 3 1/2 lbs. Thus, MERIDIA is proven effective therapy for the obese patient who needs to loose weight to decease morbidity. Nonetheless, the magnitude of the weight loss will ulti mately depend on the degree of concomitant caloric restriction and the concomitant use of a graded exercise program.

How should you take this medication?
Meridia comes as a capsule to take by mouth. It is usually taken once a day and may be taken with or without food. Follow the directions on your prescription label carefully, and ask your doctor or ph armacist to explain any part you do not understand.

Take Meridia exactly as directed. Meridia can be habit forming. Do not take a larger dose, take it more often, or for a longer period than your doctor tells you to.




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