is when you should be well on your way to a new lifestyle and ready to stop MERIDIA.

Appetite suppressants are not a substitute for proper diet. For maximum effects, this must be used in conjunction with a diet and exercise progra m.

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Precautions while Using this Medicine
It is important that your doctor check your progress at regular visits. Meridia may increase blood pressure or heart rate and your doctor will check for these effects. Your doctor may need to adjust y our dose.

If Meridia does not seem to be working well, do not increase your dosage. Check with your doctor.

Do not drink excess alcohol while taking Meridia.

Notify your do ctor as soon as possible if you develop a skin rash, hives, or other allergic symptoms.

How to Use
Meridia comes as a capsule to take by mouth. It is usually taken once a day and may be taken with or without food. Follow the directions on your prescription label carefully, and ask your doctor or ph armacist to explain any part you do not understand.

Take Meridia exactly as directed. Meridia can be habit forming. Do not take a larger dose, take it more often, or for a longer period than your doctor tells you to.

MERIDIA is a short-term drug that helps you to start losing weight and then keep on going when you are ready to carry on, on your own. Your body starts to build up a resistance to the effects of MERIDIA after a few weeks of treatment, which
When you are taking Meridia, it is especially important that your health care professional know if you are taking any of the following:

- Monoamine oxidase (MAO) inhibitor activity (isocarbo xazid [e.g., Marplan], phenelzine [e.g., Nardil], procarbazine [e.g., Matulane], selegiline [e.g., Eldepryl], tranylcypromine [e.g., Parnate])— Do not take Meridia while you are taking or within 2 wee ks of taking an MAO inhibitor, and do not take an MAO inhibitor within 2 weeks of taking Meridia . If you do, you may develop severe seizures, extremely high blood pressure, or the serotonin syndrome. Allow at least 2 weeks to pass between taking one of these medicines (Meridia or an MAO inhibitor) and taking the other

Why is this medication prescribed?
Meridia (si-BYOO-tra-meen) is used together with a reduced-calorie diet to help you lose weight and to help keep the lost weight from returning. Meridia is thought to work by increasing the activity o f certain chemicals, called norepinephrine and serotonin, in the brain. This medicine is approved for use only in people who are very overweight.

Before Using This Medicine
The presence of other medical problems may affect the use of Meridia. Make sure you tell your doctor if you have any other medical problems, especially:
- Anorexia nervosa (an eating disorder) or
- Glaucoma, narrow angle or
- High blood pressure (or history of)—Meridia may make these conditions worse
- Brain disease or damage, or mental retardation or
- Seizures (history o f)—Meridia may increase the chance of having seizures
- Gallstones (or history of)—Weight loss may make this condition worse
- Heart disease (or history of) or
- Stroke (or history of)— Increased blood pressure or heart rate caused by Meridia may make these conditions worse
- Kidney disease (severe)

What side effects can this medication cause?
Check with your doctor as soon as possible if any of the following side effects occur:

- Achiness; chills; fast or irregular heartbeat; increased blood pressure ; mental depression; pain ful menstruation; swelling of body or of feet and ankles

- Bruising or red spots or patches on skin; convulsions (seizures); excessive bleeding following injury; headache (severe); ra pidly changing moods; skin rash; weight gain (unusual)