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Other Medicines
If Nexium is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Nexium with the foll owing:

- Diazepam (Valium)
- Digoxin (Lanoxin)
- Iron salts (Ferro-Sequels)
- Ketoconazole (Nizoral)
- Warfarin (Coumadin)

There's no problem, however, with com bining antacids and Nexium; no unwanted interaction will result.

Why is this medication prescribed?
Nexium relieves heartburn and other symptoms caused by the backflow of stomach acid into the canal to the stomach (the esophagus)+m-a condition known as gastroesophageal reflux disease. It is also pre scribed to heal the damage (erosive esophagitis) that reflux disease can cause.

Prescribed in combination with the antibiotics Biaxin and Amoxil, Nexium is also used to treat the infection t hat causes most duodenal ulcers (ulcers occurring just beyond the exit from the stomach).

Like its sister drug Prilosec, Nexium works by reducing the production of stomach acid.

Side Effects of This Medicine
Rare side effects may include:
- itching, leg and body swelling, liver problems, loss of appetite, loss of taste, lymph node problems, menstrual problems, migraine, mouth and throat problems, nau sea, nervousness, nosebleed, pain, painful joints and muscles, painful urination, prickly or burning sensation, rash, rectal problems, rigidity, ringing in the ears, runny nose, sensitivity to touch, sinus problems, sleep disorders, sleepiness, sore throat, stomach bleeding, stomach pain, stomach upset, sweating, swelling, taste changes, thirst, tremors, urinary tract infection, vaginitis, vertigo , vision changes, vomiting, weakness, weight changes, worsening of arthritis, worsening of asthma, worsening of depression

How should you take this medication?
If you cannot swallow the capsule, add one tablespoon of cool, soft applesauce to an empty bowl, open one Nexium capsule, and carefully sprinkle the pellets onto the applesauce. Mix the pellets with t he applesauce and swallow the entire tablespoonful of applesauce and Nexium pellets immediately. Do not chew the pellets in the applesauce and do not save the pellets and applesauce for another dose
Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use Nexium exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Overdose
Any medication taken in excess can have serious consequences. There have been some reports of Nexium overdoses. If you suspect an overdose, seek medical attention immediately.

Symptoms of Ne xium overdose may include:
- Blurred vision, confusion, drowsiness, dry mouth, flushing, headache, nausea, rapid heartbeat, sweating

Before Using This Medicine
The effects of Nexium during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, check with your doctor.

Because Nexium is likely to appear in breast milk and could harm a nursing infant, you'll need to choose between taking Nexium or breastfeeding your baby.


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