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Significant Interactions:
If Nexium is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Nexium with the foll owing:

- Diazepam (Valium)
- Digoxin (Lanoxin)
- Iron salts (Ferro-Sequels)
- Ketoconazole (Nizoral)
- Warfarin (Coumadin)

There's no problem, however, with com bining antacids and Nexium; no unwanted interaction will result.

Symptoms of overdose
Any medication taken in excess can have serious consequences. There have been some reports of Nexium overdoses. If you suspect an overdose, seek medical attention immediately.

Symptoms of Ne xium overdose may include:
- Blurred vision, confusion, drowsiness, dry mouth, flushing, headache, nausea, rapid heartbeat, sweating

What special precautions should I follow?
Older adults¡XThis medicine has been tested and has not been shown to cause different side effects or problems in older people than it does in younger adults.

Side Effects of This Medicine
Side effects from Nexium can occur. Tell your doctor if any of these symptoms are severe or do not go away:

- headache
- diarrhea
- upset stomach
- flatulence (gas)
- sto mach pain
- constipation
- dry mouth
- change in taste

If you experience any of the following symptoms, call your doctor immediately:

- confusion
- drowsiness < br> - blurred vision
- rapid heartbeat
- sweating
- flushing

Why is this drug prescribed?
Nexium relieves heartburn and other symptoms caused by the backflow of stomach acid into the canal to the stomach (the esophagus)+m-a condition known as gastroesophageal reflux disease. It is also pre scribed to heal the damage (erosive esophagitis) that reflux disease can cause.

Prescribed in combination with the antibiotics Biaxin and Amoxil, Nexium is also used to treat the infection t hat causes most duodenal ulcers (ulcers occurring just beyond the exit from the stomach).

Like its sister drug Prilosec, Nexium works by reducing the production of stomach acid.

How should you take this medication?
If you are taking Nexium for your esophagus and other conditions in which the stomach makes too much acid, your symptoms should improve within 4 to 8 weeks. If your symptoms continue, or if they worse n, call your doctor. Your doctor may continue treatment for another 4 to 8 weeks.

If you are taking Nexium for your ulcer, your symptoms should improve within 10 days. If ulcer symptoms do no t improve, or if they worsen, call your doctor.

Do not stop taking Nexium without talking to your doctor.


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