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Special Wanring
Adverse Events Leading to Discontinuation of Treatment: - 16% (656/4126) of patients who received paroxetine in worldwide clinical trials discontinued treatment due to an adverse experience. The most
common events (reported by at least 1% of subjects) associated with discontinuation included: asthenia, headache, nausea, somnolence, insomnia and abnormal ejaculation. All other events associated wit
h discontinuation occurred at rates of 1% or less.
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What is this medicine
Paxil is used to treat depression, obsessive-compulsive disorders, panic attacks, social anxiety disorder, generalized anxiety disorder, and posttraumatic stress disorder. Paxil controlled-release (P
axil CR) is used to treat depression and panic attacks. Paxil is in a class of medications called selective serotonin reuptake inhibitors (SSRIs). It works by increasing the amounts of certain natural
substances in the brain.
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What special precautions should I follow?
Children¡XPaxil has not be shown to be safe and effective in children or adolescents, 18 years of age or younger. Children may be especially sensitive to the effects of Paxil for the treatment of depr
ssion. This may increase the chance of a child planning to commit suicide or attempting to commit suicide. Talk to your doctor about the risks and benefits of taking this medication.
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Symptoms of overdose may include:
No specific antidote is known. Treatment should consist of those general measures employed in the management of overdose with any antidepressant.
The stomach should be emptied either by the
induction of emesis, lavage or both. Following evacuation, 20 to 30 g of activated charcoal may be administered every 4 to 6 hours during the first 24 hours after ingestion. Supportive care with frequ
ent monitoring of vital signs and careful observation is indicated.
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Precautions while Using this Medicine
Paxil should be used cautiously by people with a history of manic disorders and those with high pressure in the eyes (glaucoma).
If you have a history of seizures, make sure your doctor know
s about it. Paxil should be used with caution in this situation. If you develop seizures once therapy has begun, the drug should be discontinued.
If you have a disease or condition that affe
cts your metabolism or blood circulation, make sure your doctor is aware of it. Paxil should be used cautiously in this situation.
Paxil may impair your judgment, thinking, or motor skills.
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Possible Side Effect
If you experience any of the following symptoms, call your doctor immediately:
- jaw, neck, and back muscle spasms
- slow or difficult speech
- shuffling walk
- persistent fin
e tremor or inability to sit still
- fever, chills, sore throat, or flu-like symptoms
- difficulty breathing or swallowing
- severe skin rash
- yellowing of the skin or eyes
-
irregular heartbeat
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