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Symptoms of overdose
No specific antidote is known. Treatment should consist of those general measures employed in the management of overdose with any antidepressant.
The stomach should be emptied either by the
induction of emesis, lavage or both. Following evacuation, 20 to 30 g of activated charcoal may be administered every 4 to 6 hours during the first 24 hours after ingestion. Supportive care with frequ
ent monitoring of vital signs and careful observation is indicated.
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Why is this drug prescribed?
Paxil (pa-ROX-uh-teen) is used to treat mental depression, obsessive-compulsive disorder, panic disorder, generalized anxiety disorder, social anxiety disorder (also known as social phobia), premenstr
ual dysphoric disorder (PMDD), and posttraumatic stress disorder (PTSD).
Paxil belongs to a group of medicines known as selective serotonin reuptake inhibitors (SSRIs). These medicines are th
ought to work by increasing the activity of the chemical serotonin in the brain.
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How should this medicine be used?
Swallow the controlled-release tablets whole; do not split, chew, or crush them.
Continue to take Paxil even if you feel well. Do not stop taking Paxil without talking to your doctor, especia
lly if you have taken large doses for a long time. Your doctor will probably want to decrease your dose gradually. This drug must be taken regularly for a few weeks before its full effect is felt
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Significant Interactions:
Geriatrics: - Administration of paroxetine to the elderly is associated with increased plasma levels and prolongation of the elimination half-life relative to younger adults (see Pharmacology, Pharmac
okinetics). Elderly patients should be initiated and maintained at the lowest daily dose of paroxetine which is associated with clinical efficacy.
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Adverse Effects
Commonly Observed: - The most commonly observed adverse experiences associated with the use of paroxetine and not seen at an equivalent incidence among placebo treated patients were: Nausea, somnolenc
e, sweating, tremor, asthenia, dizziness, dry mouth, insomnia and male sexual dysfunction (primarily ejaculatory delay).
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Side Effects of This Medicine
Rare side effects may include:
- Abnormal thinking, acne, alcohol abuse, allergic reaction, asthma, belching, blood and lymph abnormalities, breast pain, bronchitis, chills, colitis, difficulty s
wallowing, dry skin, ear pain, exaggerated sense of well-being, eye pain or inflammation, face swelling, fainting, generally ill feeling, hair loss, hallucinations, heart and circulation problems, hig
h blood pressure, hostility, hyperventilation, increased salivation, increased sex drive, inflamed gums, inflamed mouth or tongue, lack of emotions, menstrual problems, migraine, movement disorders, n
eck pain, nosebleeds, paranoid and manic reactions, poor coordination, respiratory infections, sensation disorders, shortness of breath
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