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Significant Interactions:
Anticoagulants: - Paroxetine should be administered with great caution to patients receiving oral anticoagulants. Preliminary data suggest that a pharmacodynamic interaction between paroxetine and war farin may result in increased bleeding in the presence of unaltered prothrombin times.

What side effects can this medication cause?
Less common side effects may include:
- Abdominal pain, abnormal dreams, abnormal vision, agitation, altered taste sensation, blurred vision, burning or tingling sensation, drugged feeling, emoti onal instability, headache, increased appetite, infection, itching, joint pain, muscle tenderness or weakness, pounding heartbeat, rash, ringing in ears, sinus inflammation, tightness in throat, twitc hing, upset stomach, urinary disorders, vomiting, weight gain, vertigo, yawning

Why is this drug prescribed?
Paxil is used to treat depression, obsessive-compulsive disorders, panic attacks, social anxiety disorder, generalized anxiety disorder, and posttraumatic stress disorder. Paxil controlled-release (P axil CR) is used to treat depression and panic attacks. Paxil is in a class of medications called selective serotonin reuptake inhibitors (SSRIs). It works by increasing the amounts of certain natural substances in the brain.

Overdosage
Overdose attempts have been reported with paroxetine; up to 850 mg alone and in combination with other agents. In cases where paroxetine was used alone, no deaths have occurred and recovery was medica lly uneventful.

Symptoms of overdosage with paroxetine include nausea, vomiting, tremor, dilated pupils, dry mouth and irritability. There are no reports of ECG abnormalities, coma or convul sions following overdosage with paroxetine alone.

Cautions
Paxil should be used cautiously by people with a history of manic disorders and those with high pressure in the eyes (glaucoma).

If you have a history of seizures, make sure your doctor know s about it. Paxil should be used with caution in this situation. If you develop seizures once therapy has begun, the drug should be discontinued.

If you have a disease or condition that affe cts your metabolism or blood circulation, make sure your doctor is aware of it. Paxil should be used cautiously in this situation.

Paxil may impair your judgment, thinking, or motor skills.

How should this medicine be used?
Take this medicine only as directed by your doctor to benefit your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer time than your doct or ordered.

Paxil may be taken with or without food or on a full or empty stomach. However, if your doctor tells you to take the medicine a certain way, take it exactly as directed.


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