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What special precautions should I follow?
If you have been taking this medicine for a long time or in large doses and you think you may have become mentally or physically dependent on it, check with your doctor.

- Some signs of depe ndence on appetite suppressants are:
- a strong desire or need to continue taking the medicine.
- a need to increase the dose to receive the effects of the medicine.
- withdrawal side e ffects (for example, mental depression, nausea or vomiting, stomach cramps or pain, trembling, unusual tiredness or weakness) when you stop taking the medicine

What side effects can this medication cause?
After you stop using this medicine, your body may need time to adjust. The length of time this takes depends on the amount of medicine you were using and how long you used it. During this time check w ith your doctor if you notice any of the following side effects:

Extreme tiredness or weakness; mental depression; nausea or vomiting; stomach cramps or pain; trembling; trouble in sleep ing or nightmares

Before Using This Medicine
Make sure you tell your doctor if you have any other medical problems, especially:
- Alcohol abuse (or history of) or
- Drug abuse or dependence (or history of)—Dependence on appetite suppr ssants may be more likely to develop
- Diabetes mellitus (sugar diabetes)—The amount of insulin or oral antidiabetic medicine that you need to take may change
- Epilepsy—Diethylpropion may ncrease the risk of having seizures
- Family history of mental illness—Mental depression or other mental illness may be more likely to occur
- Glaucoma or
- Heart or blood vessel disea e or
- High blood pressure or
- Mental illness or
- Overactive thyroid—Appetite suppressants may make the condition worse
- Kidney disease

Precautions Before Using This Medicine
Children—Studies on these medicines have been done only in adult patients, and there is no specific information comparing use of Phendimetrazine in children with use in other age groups. The use of t ese medicines by children younger than 16 years of age is not recommended.

Older adults—Many medicines have not been studied specifically in older people. Therefore, it may not be known whe her they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of appetite suppressant s in the elderly with use in other age groups.

Drug Interactions
It is especially important that your health care professional know if you are taking any of the following:
- Amantadine (e.g., Symmetrel) or
- Amphetamines or
- Caffeine (e.g., NoDoz) o r
- Chlophedianol (e.g., Ulone) or
- Cocaine or
- Medicine for asthma or other breathing problems or
- Medicine for colds, sinus problems, or hay fever or other allergies or
- Methylphenidate (e.g., Ritalin) or
- Nabilone (e.g., Cesamet) or
- Pemoline (e.g., Cylert)
- Appetite suppressants (diet pills), other or
- There have been some serious unwanted ef fects on the hearts of people who used two different appetite suppressants together
- Monoamine oxidase (MAO) inhibitor activity

Why is this medication prescribed?
Phendimetrazine are used in the short-term treatment of obesity. Their appetite-reducing effect tends to decrease after a few weeks. Because of this, these medicines are useful only during the first f ew weeks of a weight-loss program. The Phendimetrazine can help you to lose weight while you are learning new ways to eat and to exercise. Changes in eating habits and activity level must be developed and continued long-term in order for you to continue losing weight and to keep the lost weight from returning