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Possible Side Effect
After you stop using this medicine, your body may need time to adjust. The length of time this takes depends on the amount of medicine you were using and how long you used it. During this time check w ith your doctor if you notice any of the following side effects:

Extreme tiredness or weakness; mental depression; nausea or vomiting; stomach cramps or pain; trembling; trouble in sleep ing or nightmares

Cautions
If you have been taking this medicine for a long time or in large doses and you think you may have become mentally or physically dependent on it, check with your doctor.

- Some signs of depe ndence on appetite suppressants are:
- a strong desire or need to continue taking the medicine.
- a need to increase the dose to receive the effects of the medicine.
- withdrawal side e ffects (for example, mental depression, nausea or vomiting, stomach cramps or pain, trembling, unusual tiredness or weakness) when you stop taking the medicine

Overdosage
Abuse of a sympathomimetic appetite suppressant (taking the medicine in larger doses or taking it more frequently or for a longer time than the doctor ordered) can cause the following side effects:
Changes in personality; excessive, excited activity; irritability (severe); mental illness (severe), similar to schizophrenia; skin disease; trouble in sleeping (severe)

Other medical problems
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it may do. This is a decision you and your doctor will make. For Phendimetrazine, the following should be considered:

Allergies¡XTell your doctor if you have ever had any unusual or allergic reaction to this medicine or amphetamine, dextroamphetamine, ephedrine, epinephrine, isoproterenol, met proterenol, methamphetamine, norepinephrine, phenylephrine, phenylpropanolamine, pseudoephedrine, terbutaline, or other appetite suppressants. Also tell your health care professional if you are allerg ic to any other substances, such as foods, preservatives, or dyes.

Possible food and drug interactions when taking this medication
Tell your doctor if you are taking any of the following:
- Appetite suppressants (diet pills), other or
- There have been some serious unwanted effects on the hearts of people who used two different appetite suppressants together
- Amantadine (e.g., Symmetrel) or
- Cocaine or
- Medicine for asthma or other breathing problems or
- Medicine for colds, sinus problems, or hay fever or other allergies or
- Methylphenidate (e.g., Ritalin) or
- Nabilone (e.g., Cesamet) or
- Pemoline (e.g., Cylert)
- Monoamine oxidase (MAO) inhibitor activity
- Amp hetamines or
- Caffeine (e.g., NoDoz) or
- Chlophedianol (e.g., Ulone)

Before Using This Medicine
Make sure you tell your doctor if you have any other medical problems, especially:
- Alcohol abuse (or history of) or
- Drug abuse or dependence (or history of)¡XDependence on appetite suppr ssants may be more likely to develop
- Diabetes mellitus (sugar diabetes)¡XThe amount of insulin or oral antidiabetic medicine that you need to take may change
- Epilepsy¡XDiethylpropion may ncrease the risk of having seizures
- Family history of mental illness¡XMental depression or other mental illness may be more likely to occur
- Glaucoma or
- Heart or blood vessel disea e or
- High blood pressure or
- Mental illness or
- Overactive thyroid¡XAppetite suppressants may make the condition worse
- Kidney disease


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