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What special precautions should I follow?
Allergies¡XTell your doctor if you have ever had any unusual or allergic reaction to acitretin, etretinate, isoRetin-A, Retin-A, or vitamin A preparations. Also tell your health care professional if y u are allergic to any other substances, such as preservatives or dyes.

Description
It is very important that you use this medicine only as directed. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause irri tation of the skin.

Do not apply this medicine to windburned or sunburned skin or on open wounds.

Do not use this medicine in or around the eyes or lips, or inside of the nose. Spre ad the medicine away from these areas when applying. If the medicine accidentally gets on these areas, wash with water at once.

This medicine usually comes with patient directions. Read them carefully before using the medicine.

What is this Drug
For patients using Retin-A for the treatment of acne:
- Regular use of water-based creams or lotions helps to reduce skin irritation or dryness that may be caused by the use of Retin-A.
For patients using Retin-A for the treatment of fine wrinkling, dark spots, and rough skin caused by the sun:
- This medicine should be used as part of an ongoing program to avoid further damage to y our skin from the sun. This program includes staying out of the sun when possible or wearing proper clothing or hats to protect your skin from sunlight.
- Regular use of oil-based creams or lotio ns helps to reduce skin irritation or dryness caused by the use of Retin-A.

Possible food and drug interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to c hange the dose, or other precautions may be necessary. Tell your health care professional if you are using any other topical prescription or nonprescription (over-the-counter [OTC]) medicine that is t o be applied to the same area of the skin. When you are using topical Retin-A, it is especially important that your health care professional know if you are taking any of the following:

- Ac itretin (e.g., Soriatane)
- Etretinate (e.g., Tegison)
- Retin-A, oral ¡XMay increase chance of getting severe dryness or redness of skin

Special warnings about this medication
During the first 6 months of use, avoid overexposing the treated areas to sunlight, wind, or cold weather. The skin will be more prone to sunburn, dryness, or irritation, especially during the first 2 or 3 weeks. However, you should not stop using this medicine unless the skin irritation becomes too severe. Do not use a sunlamp .

Possible Side Effect
Although this use is not included in product labeling, Retin-A is used in certain patients with the following medical conditions:

- Keratosis follicularis (skin disorder of small, red bumps)
- Verruca plana (flat warts)


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