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Side Effects
In some animal studies, Retin-A has been shown to cause skin tumors to develop faster when the treated area is exposed to ultraviolet light (sunlight or artificial sunlight from a sunlamp). Other stud ies have not shown the same result and more studies need to be done. It is not known if Retin-A causes skin tumors to develop faster in humans.

Check with your doctor as soon as possible if a ny of the following side effects occur:

- Burning feeling or stinging skin (severe); lightening of skin of treated area, unexpected; peeling of skin (severe); redness of skin (severe) ; u nusual dryness of skin (severe)

- Darkening of treated skin

Proper Use of This Medicine
Make sure you tell your doctor if you have any other medical problems, especially:
- Dermatitis, seborrheic or
- Eczema or
- Sunburn—Use of this medicine may cause or increase the irr tation associated with these problems

Description
Do not use any other topical medications, especially benzoyl peroxide, salicylic acid (wart remover), and dandruff shampoos containing sulfur or resorcinol unless your doctor directs you to do so. If you have used any of these topical medications recently, ask your doctor if you should wait before using Retin-A

Why is this drug prescribed?
Retin-A is used to treat acne. It works partly by keeping skin pores clear.

One of the Retin-A creams is used to treat fine wrinkles, dark spots, or rough skin on the face caused by damaging rays of the sun. It works by lightening the skin, replacing older skin with newer skin, and by slowing down the way the body removes skin cells that may have been harmed by the sun. Retin-A works bes t when used within a skin care program that includes protecting the treated skin from the sun. However, it does not completely or permanently erase these skin problems or greatly improve more obvious changes in the skin, such as deep wrinkles caused by sun or the natural aging process.

Precautions Before Using This Medicine
Children—Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of this medicine in children with use in other age groups. Children are unl kely to have skin problems due to the sun. In older children treated for acne, Retin-A is not expected to cause different side effects or problems than it does in other age groups.

Possible food and drug interactions when taking this medication
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to c hange the dose, or other precautions may be necessary. Tell your health care professional if you are using any other topical prescription or nonprescription (over-the-counter [OTC]) medicine that is t o be applied to the same area of the skin. When you are using topical Retin-A, it is especially important that your health care professional know if you are taking any of the following:

- Ac itretin (e.g., Soriatane)
- Etretinate (e.g., Tegison)
- Retin-A, oral —May increase chance of getting severe dryness or redness of skin