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Side Effects
In some animal studies, Retin-A has been shown to cause skin tumors to develop faster when the treated area is exposed to ultraviolet light (sunlight or artificial sunlight from a sunlamp). Other stud ies have not shown the same result and more studies need to be done. It is not known if Retin-A causes skin tumors to develop faster in humans.

Check with your doctor as soon as possible if a ny of the following side effects occur:

- Burning feeling or stinging skin (severe); lightening of skin of treated area, unexpected; peeling of skin (severe); redness of skin (severe) ; u nusual dryness of skin (severe)

- Darkening of treated skin

Possible food and drug interactions when taking this medication
Tell your health care professional if you are using any other topical prescription or nonprescription (over-the-counter [OTC]) medicine that is to be applied to the same area of the skin. When you are using topical Retin-A, it is especially important that your health care professional know if you are taking any of the following:

- Acitretin (e.g., Soriatane)
- Etretinate (e.g., Tegi son)
- Retin-A, oral ¡XMay increase chance of getting severe dryness or redness of skin

Special warnings about this medication
Unless your doctor tells you otherwise, it is especially important to avoid using the following skin products on the same area as Retin-A:

- Any other topical acne product or skin product co ntaining a peeling agent (such as benzoyl peroxide, resorcinol, salicylic acid, or sulfur)
- Hair products that are irritating, such as permanents or hair removal products
- Skin products th at cause sensitivity to the sun, such as those containing spices or limes
- Skin products containing a large amount of alcohol, such as astringents, shaving creams, or after-shave lotions
- Skin products that are too drying or abrasive, such as some cosmetics, soaps, or skin cleansers

What Is It
Do not use any other topical medications, especially benzoyl peroxide, salicylic acid (wart remover), and dandruff shampoos containing sulfur or resorcinol unless your doctor directs you to do so. If you have used any of these topical medications recently, ask your doctor if you should wait before using Retin-A

How to Use
Make sure you tell your doctor if you have any other medical problems, especially:
- Dermatitis, seborrheic or
- Eczema or
- Sunburn¡XUse of this medicine may cause or increase the irr tation associated with these problems

Why is this drug prescribed?
For patients using Retin-A for the treatment of acne:
- Regular use of water-based creams or lotions helps to reduce skin irritation or dryness that may be caused by the use of Retin-A.
For patients using Retin-A for the treatment of fine wrinkling, dark spots, and rough skin caused by the sun:
- This medicine should be used as part of an ongoing program to avoid further damage to y our skin from the sun. This program includes staying out of the sun when possible or wearing proper clothing or hats to protect your skin from sunlight.
- Regular use of oil-based creams or lotio ns helps to reduce skin irritation or dryness caused by the use of Retin-A.


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