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Before Using This Medicine
Older adults¡XValtrex has been used in elderly patients and has not been shown to cause different side effects or problems in older people than it does in younger adults. Elderly patients are at a hig risk for dehydration and should drink plenty of fluids.

What is this medicine
Valtrex (val-ay-SYE-kloe-veer) is used to treat the symptoms of herpes zoster (also known as shingles), a herpes virus infection of the skin; it is also used to treat and prevent genital herpes infect ions. In your body, Valtrex becomes the anti-herpes medicine, acyclovir. Although Valtrex will not cure shingles or genital herpes, it does help relieve the pain and discomfort and helps the sores hea l faster.

Significant Interactions:
If you are taking Valtrex with certain other drugs, the effect of either drug could be increased, decreased, or altered. Check with your doctor before combining Valtrex with cimetidine (Tagamet) and/o r probenecid (Benemid).

How should you take this medication?
Valtrex comes as a tablet to take by mouth. It is usually taken every 8 hours (three times a day) for 7 days to treat shingles. To treat genital herpes it is usually taken twice a day for 5 days. Foll ow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Valtrex exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Use this medication as soon as possible after symptoms appear.

What side effects can this medication cause?
Check with your doctor as soon as possible if the following side effect occurs:

- Painful menstruation, including abdominal cramps, diarrhea, or nausea

- Black, tarry stools; ches t pain; chills; cough; decreased frequency/output of urine; fever; flu-like symptoms; headache; lower back/side pain; reduced mental alertness; shortness of breath; unusual tiredness; yello w eyes or skin

- Back, leg or stomach pains; changes in behavior, especially in interactions with other people; difficulty breathing or swallowing; fast, pounding, or irregular heartbeat ; high blood pressure; itching; lightheadedness when getting up from a lying or sitting position; redness of skin ;

Cautions
High doses of Valtrex have proved dangerous in people whose immune system is compromised because of HIV infection, bone marrow transplant, or kidney transplant.

If your kidneys are not funct ioning properly, or you are taking drugs that may damage the kidneys such as Neomycin or Streptomycin, Valtrex can make your condition worse or affect your central nervous system (brain and spinal cor d).

Effects on the central nervous system are more common in older adults, leading to such symptoms as agitation, confusion, and hallucinations. Their kidneys are also more likely to be affe cted; and those with kidney problems need a smaller dose. Older adults tend to suffer the pain of shingles for a longer time after healing has begun.


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