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Possible food and drug interactions when taking this medication
If you are taking Valtrex with certain other drugs, the effect of either drug could be increased, decreased, or altered. Check with your doctor before combining Valtrex with cimetidine (Tagamet) and/o r probenecid (Benemid).

Special warnings about this medication
The presence of other medical problems may affect the use of Valtrex. Make sure you tell your doctor if you have any other medical problems, especially:
- Advanced human immunodeficiency virus (H IV) infection or
- Bone marrow transplantation or
- Kidney transplantation¡XPatients with these medical problems may have an increased risk of severe side effects
- Kidney disease¡XKidn disease may increase blood levels of this medicine, increasing the chance of side effects

Why is this drug prescribed?
Valtrex is used to treat certain herpes infections, including herpes zoster (the painful rash known as shingles), genital herpes, and herpes cold sores on the face and lips.

How should this medicine be used?
Valtrex comes as a tablet to take by mouth. It is usually taken every 8 hours (three times a day) for 7 days to treat shingles. To treat genital herpes it is usually taken twice a day for 5 days. Foll ow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Valtrex exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Use this medication as soon as possible after symptoms appear.

What side effects may occur?
Check with your doctor as soon as possible if the following side effect occurs:

- Painful menstruation, including abdominal cramps, diarrhea, or nausea

- Black, tarry stools; ches t pain; chills; cough; decreased frequency/output of urine; fever; flu-like symptoms; headache; lower back/side pain; reduced mental alertness; shortness of breath; unusual tiredness; yello w eyes or skin

- Back, leg or stomach pains; changes in behavior, especially in interactions with other people; difficulty breathing or swallowing; fast, pounding, or irregular heartbeat ; high blood pressure; itching; lightheadedness when getting up from a lying or sitting position; redness of skin ;

Other medical problems
Allergies¡XTell your doctor if you have ever had any unusual or allergic reaction to Valtrex or acyclovir. Also tell your health care professional if you are allergic to any other substances, such as oods, sulfites or other preservatives, or dyes.


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