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Pregnancy¡XOne study looked at the babies of 147 women who took Zoloft either at the beginning of pregnancy or through the entire pregnancy. This study found no harmful effects of Zoloft on the babies However, more study is needed to be sure that Zoloft is safe to use during pregnancy. Before taking this medicine, make sure your doctor knows if you are pregnant or if you may become pregnant.

Why is this drug prescribed?
Zoloft is prescribed for major depressive disorder¡Xa persistently low mood that interferes with everyday living. Symptoms may include loss of interest in your usual activities, disturbed sleep, chang in appetite, constant fidgeting or lethargic movement, fatigue, feelings of worthlessness or guilt, difficulty thinking or concentrating, and recurrent thoughts of suicide.

Symptoms of overdose may include:
Establish and maintain an airway, insure adequate oxygenation and ventilation. Activated charcoal, which may be used with sorbitol, may be as or more effective than emesis or lavage, and should be con sidered in treating overdose.

Cardiac and vital signs monitoring are recommended along with general symptomatic and supportive measures.

There are no specific antidotes for sertral ine.

Due to the large volume of distribution of sertraline, forced diuresis, dialysis, hemoperfusion, and exchange transfusion are unlikely to be of benefit.

In managing overdose, the possibility of multiple drug involvement must be considered.

Adverse Effects
Disorders of Skin and Appendages: - Infrequent: Acne, alopecia, pruritus, erythematous rash, maculopapular rash, dry skin. Rare: Bullous eruption, dermatitis, erythema multiforme, abnormal hair textur e, hypertrichosis, photosensitivity reaction, follicular rash, skin discoloration, abnormal skin odor, urticaria.

Possible Side Effect
Less common or rare side effects may include:
- frequent urination, hair loss, heart attack, hemorrhoids, hiccups, high blood pressure, high pressure within the eye (glaucoma), hearing problems, hot flushes, impotence, inability to stay seated, increased appetite, increased salivation, increased sex drive, inflamed nasal passages, inflammation of the penis, intolerance to light, irregular he artbeat, itching, joint pains, kidney failure, lack of coordination, lack of sensation, leg cramps, menstrual problems, low blood pressure, migraine, movement problems,

How should you take this medication?
Zoloft comes as a tablet and concentrate to take by mouth. It is usually taken once daily and may be taken with or without food. Follow the directions on your prescription label carefully, and ask you r doctor or pharmacist to explain any part you do not understand. Take Zoloft exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Continu e to take Zoloft even if you feel well. Do not stop taking Zoloft without talking to your doctor, especially if you have taken large doses for a long time. Your doctor probably will want to decrease y our dose gradually. This drug must be taken regularly for a few weeks before its full effect is felt.


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