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Proper Use of This Medicine
Zoloft concentrate must be diluted before use. Immediately before taking it, use the provided dropper to remove the amount of concentrate your doctor has directed you to take. Mix the concentrate with 4 ounces (1/2 cup) of water, ginger ale, lemon or lime soda, lemonade, or orange juice. Drink immediately. Do not mix the concentrate with any liquids other than the ones listed.

Precautions Before Using This Medicine
Make sure you tell your doctor if you have any other medical problems, especially:
- Brain disease or damage or
- Mental retardation or
- Seizure disorders (history of)¡XThe risk of se ures may be increased
- Kidney disease¡XIt is not known whether the chance of side effects will be increased
- Liver disease¡XHigher blood levels of Zoloft may occur, increasing the chance o side effects. Your doctor may want you to take a lower dose or to take your doses less often than a person without liver disease
- Mania (history of)¡XMay be activated
- Weight loss¡XZoloft y cause weight loss. This weight loss is usually small, but if a large weight loss occurs, it may be harmful in some patients

What side effects may occur?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Zoloft.

More common side effects may include:
Abdominal pain, agitation, anxiety, constipation, decreased sex drive, diarrhea or loose stools, difficulty with ejaculation, dizziness, dry mouth, fati gue, gas, headache, decreased appetite, increased sweating, indigestion, insomnia, nausea, nervousness, pain, rash, sleepiness, sore throat, tingling or pins and needles, tremor, vision problems, vomi ting

Adverse Effects
Psychiatric Disorders: - Infrequent: Abnormal dreams, aggressive reaction, amnesia, apathy, delusion, depersonalization, depression, aggravated depression, emotional lability, euphoria, hallucination, neurosis, paranoid reaction, suicide attempt (including suicidal ideation), teeth-grinding, abnormal thinking. Rare: Hysteria, somnambulism withdrawal syndrome.

What is this Drug
In addition, Zoloft is used in the treatment of obsessive-compulsive disorder--symptoms of which include unwanted thoughts that won't go away and an irresistible urge to keep repeating certain actions , such as hand-washing or counting. It is also prescribed for the treatment of panic disorder (unexpected attacks of overwhelming anxiety, accompanied by fear of their return), and for posttraumatic s tress disorder (re-experiencing a dangerous or life-threatening event through intrusive thoughts, flashbacks, and intense psychological distress).

Overdose
Establish and maintain an airway, insure adequate oxygenation and ventilation. Activated charcoal, which may be used with sorbitol, may be as or more effective than emesis or lavage, and should be con sidered in treating overdose.

Cardiac and vital signs monitoring are recommended along with general symptomatic and supportive measures.

There are no specific antidotes for sertral ine.

Due to the large volume of distribution of sertraline, forced diuresis, dialysis, hemoperfusion, and exchange transfusion are unlikely to be of benefit.

In managing overdose, the possibility of multiple drug involvement must be considered.


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