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What side effects may occur?
Check with your doctor as soon as possible if any of the following side effects occur:

- Decreased sexual desire or ability

- Breast tenderness or enlargement; fast or irregular h eartbeat; fast talking and excited feelings or actions that are out of control; fever ; inability to sit still; low blood sodium (confusion, convulsions [seizures], drowsiness, dryness of mouth, i ncreased thirst, lack of energy); nose bleeds ; red or purple spots on skin; restlessness; serotonin syndrome (diarrhea, fever, increased sweating, mood or behavior changes, overactive reflexes, r acing heartbeat, restlessness, shivering or shaking); skin rash, hives, or itching; unusual or sudden body or facial movements or postures;

How should this medicine be used?
Take this medicine only as directed by your doctor, to benefit your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer time than your doc tor ordered.

Zoloft may be taken with or without food on a full or empty stomach. If your doctor tells you to take it a certain way, follow your doctor's instructions.

You may have to take Zoloft for 4 weeks or longer before you begin to feel better. Your doctor should check your progress at regular visits during this time. Also, if you are taking this medicine for depression, y ou may need to keep taking it for 6 months or longer to help prevent the return of the depression.

Management of Overdoses:
Establish and maintain an airway, insure adequate oxygenation and ventilation. Activated charcoal, which may be used with sorbitol, may be as or more effective than emesis or lavage, and should be con sidered in treating overdose.

Cardiac and vital signs monitoring are recommended along with general symptomatic and supportive measures.

There are no specific antidotes for sertral ine.

Due to the large volume of distribution of sertraline, forced diuresis, dialysis, hemoperfusion, and exchange transfusion are unlikely to be of benefit.

In managing overdose, the possibility of multiple drug involvement must be considered.

What Is It
In addition, Zoloft is used in the treatment of obsessive-compulsive disorder--symptoms of which include unwanted thoughts that won't go away and an irresistible urge to keep repeating certain actions , such as hand-washing or counting. It is also prescribed for the treatment of panic disorder (unexpected attacks of overwhelming anxiety, accompanied by fear of their return), and for posttraumatic s tress disorder (re-experiencing a dangerous or life-threatening event through intrusive thoughts, flashbacks, and intense psychological distress).

Before Taking This Medicine
Children¡XZoloft has been tested in children 6 to 17 years of age with obsessive-compulsive disorder. In effective doses, this medicine has not been shown to cause different side effects or problems t an it does in adults. However, Zoloft can cause a decrease in appetite and children who take this medicine for a long time should have their growth and body weight measured by the doctor at regular vi sits.
Zoloft must be used with caution in children with depression. Studies have shown occurrences of children thinking about suicide or attempting suicide in clinical trials for this medicine. Mor e study is needed to be sure Zoloft is safe and effective in children.

Special Wanring
Disorders of Skin and Appendages: - Infrequent: Acne, alopecia, pruritus, erythematous rash, maculopapular rash, dry skin. Rare: Bullous eruption, dermatitis, erythema multiforme, abnormal hair textur e, hypertrichosis, photosensitivity reaction, follicular rash, skin discoloration, abnormal skin odor, urticaria.


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