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Overdose
Human Experience:
There have been 3 cases of sertraline overdosage (approximately 4 to 10 times the maximum recommended daily dose). These 3 patients recovered completely without the need for spec ific therapy

What Is It
Zoloft is a member of the family of drugs called "selective serotonin re-uptake inhibitors." Serotonin is one of the chemical messengers believed to govern moods. Ordinarily, it is quickly reabsorbed after its release at the junctures between nerves. Re-uptake inhibitors such as Zoloft slow this process, thereby boosting the levels of serotonin available in the brain.

How should this medicine be used?
Take this medicine only as directed by your doctor, to benefit your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer time than your doc tor ordered.

Zoloft may be taken with or without food on a full or empty stomach. If your doctor tells you to take it a certain way, follow your doctor's instructions.

You may have to take Zoloft for 4 weeks or longer before you begin to feel better. Your doctor should check your progress at regular visits during this time. Also, if you are taking this medicine for depression, y ou may need to keep taking it for 6 months or longer to help prevent the return of the depression.

Adverse Effects
Disorders of Skin and Appendages: - Infrequent: Acne, alopecia, pruritus, erythematous rash, maculopapular rash, dry skin. Rare: Bullous eruption, dermatitis, erythema multiforme, abnormal hair textur e, hypertrichosis, photosensitivity reaction, follicular rash, skin discoloration, abnormal skin odor, urticaria.

What special precautions should I follow?
When you are taking Zoloft, it is especially important that your health care professional know if you are taking any of the following:

- Venlafaxine (e.g., Effexor)¡XUsing these medicines th Zoloft may increase the chance of developing a rare, but very serious, unwanted effect known as the serotonin syndrome. This syndrome may cause confusion, diarrhea, fever, poor coordination, restle ssness, shivering, sweating, talking or acting with excitement you cannot control, trembling or shaking, or twitching. If you develop these symptoms, contact your doctor as soon as possible
- Dig itoxin (e.g., Crystodigin)

Possible Side Effect
Less common or rare side effects may include:
- frequent urination, hair loss, heart attack, hemorrhoids, hiccups, high blood pressure, high pressure within the eye (glaucoma), hearing problems, hot flushes, impotence, inability to stay seated, increased appetite, increased salivation, increased sex drive, inflamed nasal passages, inflammation of the penis, intolerance to light, irregular he artbeat, itching, joint pains, kidney failure, lack of coordination, lack of sensation, leg cramps, menstrual problems, low blood pressure, migraine, movement problems,


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