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What is this medicine
Zyban (Wellbutrin, Wellbutrin SR), an antidepressant (mood elevator), is used to treat depression. Zyban (Zyban) is used to help people stop smoking

What side effects can this medication cause?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Zyban.
< br> The most common side effects are:
Dry mouth and sleeplessness
These are generally mild and usually disappear after a few weeks. If you have difficulty sleeping, avoid taking Zyban close t o bedtime and ask your doctor about reducing your dosage.

More common side effects may include:
Abdominal pain, abnormal dreams, anxiety, constipation, diarrhea, disturbed concentration , dizziness, joint pain, increased cough, itching, nasal inflammation, nausea, nervousness, rash, sore throat

Symptoms of overdose may include:
It is especially important to check with your doctor before combining Zyban with the following:

- Alcohol
- Amantadine (Symmetrel)
- Antidepressants such as Norpramin, Pamelor, Pa xil, Prozac, Tofranil, and Zoloft
- Beta blockers (heart and blood pressure medications) such as Inderal, Lopressor, and Tenormin
- Carbamazepine (Tegretol)
- Cimetidine (Tagamet)
- Cyclophosphamide (Cytoxan)
- Heart-stabilizing drugs such as Rythmol and Tambocor
- Levodopa (Dopar, Larodopa, Sinemet)
- Major tranquilizers such as Haldol, Risperdal and Thorazine < br> - MAO inhibitors such as the antidepressants Nardil and Parnate
- Orphenadrine (Norflex)
- Phenobarbital
- Phenytoin (Dilantin)

Drug Interactions
When you are taking Zyban, it is especially important that your health care professional know if you are taking any of the following:

- Tricyclic antidepressants (amitriptyline [e.g., Elavil ], amoxapine [e.g., Asendin], clomipramine [e.g., Anafranil], desipramine [e.g., Pertofrane], doxepin [e.g., Sinequan], imipramine [e.g., Tofranil], nortriptyline [e.g., Aventyl], protriptyline [e.g., Vivactil], trimipramine [e.g., Surmontil]) or
-
- Monoamine oxidase (MAO) inhibitor activity (isocarboxazid [e.g., Marplan], phenelzine [e.g., Nardil], procarbazine [e.g., Matulane], selegi line [e.g., Eldepryl], tranylcypromine [e.g., Parnate])¡X Do not take Zyban while you are taking or within 14 days of taking an MAO inhibitor

Before Taking This Medicine
Pregnancy¡XStudies have not been done in pregnant women. However, Zyban has not been reported to cause birth defects or other problems in animal studies.

What special precautions should I follow?
Drinking of alcoholic beverages should be limited or avoided, if possible, while taking Zyban. This will help prevent seizures.

This medicine may cause some people to feel a false sense of we ll-being, or to become drowsy, dizzy, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerou s if you are dizzy or are not alert and clearheaded.


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