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Other medical problems
Zyban has not been tested in pregnant women. If you are pregnant or plan to become pregnant, do your best to quit smoking with the aid of counseling and support before turning to drug therapy. For the sake of the baby, you should avoid smoking or taking nicotine in any other form while pregnant.

Zyban appears in breast milk and could affect a nursing infant. Ask your doctor whether it wi ll be better to discontinue the medication or to stop breastfeeding.

Overdose
It is especially important to check with your doctor before combining Zyban with the following:

- Alcohol
- Amantadine (Symmetrel)
- Antidepressants such as Norpramin, Pamelor, Pa xil, Prozac, Tofranil, and Zoloft
- Beta blockers (heart and blood pressure medications) such as Inderal, Lopressor, and Tenormin
- Carbamazepine (Tegretol)
- Cimetidine (Tagamet)
- Cyclophosphamide (Cytoxan)
- Heart-stabilizing drugs such as Rythmol and Tambocor
- Levodopa (Dopar, Larodopa, Sinemet)
- Major tranquilizers such as Haldol, Risperdal and Thorazine < br> - MAO inhibitors such as the antidepressants Nardil and Parnate
- Orphenadrine (Norflex)
- Phenobarbital
- Phenytoin (Dilantin)

Cautions
Your doctor should check your progress at regular visits, especially during the first few months of treatment with this medicine. The amount of Zyban you take may have to be changed often to meet the needs of your condition and to help avoid unwanted effects.

Do not take Zyban within 14 days of taking an MAO inhibitor.

Zyban is sold under different brand names for different uses. If you are already taking medicine for mental depression or to help you stop smoking, discuss this with your health care professional before taking Zyban. It is very important that you receive only o ne prescription for Zyban at a time.

How should you take this medication?
Treatment with this drug begins while you are still smoking. Zyban needs about a week to reach an effective level in your body; so to improve your chance of success, you should not attempt to quit unt il the second week of treatment. Set a firm date for quitting. If you are still smoking after that date, your odds of breaking the habit will be worse. You should keep taking Zyban for 7 to 12 weeks.

You can use nicotine patches along with Zyban. However, combining the two treatments can raise your blood pressure, so it's important to tell your doctor if you plan to use both. Do not smok e while using a patch, because too much nicotine can cause serious side effects.

Side Effects
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Zyban.
< br> The most common side effects are:
Dry mouth and sleeplessness
These are generally mild and usually disappear after a few weeks. If you have difficulty sleeping, avoid taking Zyban close t o bedtime and ask your doctor about reducing your dosage.

More common side effects may include:
Abdominal pain, abnormal dreams, anxiety, constipation, diarrhea, disturbed concentration , dizziness, joint pain, increased cough, itching, nasal inflammation, nausea, nervousness, rash, sore throat

Why is this medication prescribed?
Zyban is a pharmaceutical, prescription antidepressant which acts directly on the brain and other nerve cells. It is also used to treat ADHD (Attention Deficit Disorder), Bipolar depression, chronic f atigue syndrome, cocaine addiction, nicotine addiction, and lower back pain.

Zyban generally comes in 75mg and 100mg tablets. A sustained released form (Wellbutrin SR) comes in 100mg (blue), 150mg (purple), and 200mg (light pink) tablets. A new Wellbutrin XL comes in 150 & 300mg tablets (creamy white to pale yellow).

It has been associated with possible liver and kidney damage as well as seizures in .4% of the population.