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Other Medicines
When you are taking Zyban, it is especially important that your health care professional know if you are taking any of the following:

- Alcohol or
- Antipsychotics (medicine for mental illness) or
- Corticosteriods(cortisone-like medicine) or
- Fluoxetine (e.g., Prozac) or
- Lithium (e.g., Lithane) or
- Maprotiline (e.g., Ludiomil) or
- Theophylline (e.g., S omophyllin-T) or
- Trazodone (e.g., Desyrel) or
- Ritonavir (e.g., Norvir)¡XUsing these medicines with Zyban may increase the risk of seizures

How should this medicine be used?
Treatment with this drug begins while you are still smoking. Zyban needs about a week to reach an effective level in your body; so to improve your chance of success, you should not attempt to quit unt il the second week of treatment. Set a firm date for quitting. If you are still smoking after that date, your odds of breaking the habit will be worse. You should keep taking Zyban for 7 to 12 weeks.

You can use nicotine patches along with Zyban. However, combining the two treatments can raise your blood pressure, so it's important to tell your doctor if you plan to use both. Do not smok e while using a patch, because too much nicotine can cause serious side effects.

What side effects can this medication cause?
Side effects from Zyban are common:

- drowsiness
- weakness or tiredness
- excitement or anxiety
- dry mouth
- insomnia
- nightmares
- change in appetite or wei ght

Tell your doctor if any of these symptoms are severe or do not go away:

- frequent urination
- difficulty urinating
- constipation
- blurred vision
- change in sex drive or ability
- excessive sweating
- headaches

If you experience any of the following symptoms, call your doctor immediately:

- seizures or tremors
- loss of coordination
- fever
- severe skin rash
- itching
- hives
- chest pain
- shortness of breath

What special precautions should I follow?
Drinking of alcoholic beverages should be limited or avoided, if possible, while taking Zyban. This will help prevent seizures.

This medicine may cause some people to feel a false sense of we ll-being, or to become drowsy, dizzy, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerou s if you are dizzy or are not alert and clearheaded.

What special precautions should I follow?
Older adults¡XThis medicine has been tested in a limited number of patients 60 years of age and older and has not been shown to cause different side effects or problems in older people than it does in younger adults.

Overdosage
It is especially important to check with your doctor before combining Zyban with the following:

- Alcohol
- Amantadine (Symmetrel)
- Antidepressants such as Norpramin, Pamelor, Pa xil, Prozac, Tofranil, and Zoloft
- Beta blockers (heart and blood pressure medications) such as Inderal, Lopressor, and Tenormin
- Carbamazepine (Tegretol)
- Cimetidine (Tagamet)
- Cyclophosphamide (Cytoxan)
- Heart-stabilizing drugs such as Rythmol and Tambocor
- Levodopa (Dopar, Larodopa, Sinemet)
- Major tranquilizers such as Haldol, Risperdal and Thorazine < br> - MAO inhibitors such as the antidepressants Nardil and Parnate
- Orphenadrine (Norflex)
- Phenobarbital
- Phenytoin (Dilantin)


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