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What side effects can this medication cause?
Less common side effects may include:
Abnormal thinking, allergic reaction, bronchitis, changes in taste, difficulty breathing, dry skin, fever, hives, hot flashes, increased appetite or loss of appetite, increased blood pressure, migraine, mouth ulcers, muscle pain, neck pain, nosebleed, ringing in the ears, shakiness, sinus inflammation, sleepiness, throbbing heartbeat

Rare side ef fects may include:
Chest pain, feeling of unhappiness, thirst, swelling of the face

If you are using the oral concentrate form of Zoloft, do not take disulfiram (Antabuse)
If you ar e using the oral concentrate form of Zoloft, do not take disulfiram (Antabuse)

Why is this drug prescribed?
Zyban is a nicotine-free quit-smoking aid. Instead of nicotine, it contains the same active ingredient as the antidepressant medication Wellbutrin. It works by boosting the levels of several chemical messengers in the brain. With more of these chemicals at work, you experience a reduction in nicotine withdrawal symptoms and a weakening of the urge to smoke. More than a third of the people who take Zyban while participating in a support program are able to quit smoking for at least 1 month. Zyban can also prove helpful when people with conditions such as chronic bronchitis and emphysema decide it's time to quit.

Management of Overdoses:
Quitting smoking, with or without Zyban treatment, could change the way your body metabolizes certain drugs, for example, theophylline and warfarin (Coumadin). Make sure your doctor knows all the pres cription and over-the-counter medicines you're taking.

How should this medicine be used?
If you take several doses per day, take the missed dose as soon as you remember it and take any remaining doses for that day at evenly spaced intervals. However, if it is almost time for the next dose , skip the missed dose and continue your regular dosing schedule.

If you take Zyban once a day at bedtime and do not remember to take it until the next morning, skip the missed dose. Do not t ake a double dose to make up for a missed one.

Other Medicines
When you are taking Zyban, it is especially important that your health care professional know if you are taking any of the following:

- Tricyclic antidepressants (amitriptyline [e.g., Elavil ], amoxapine [e.g., Asendin], clomipramine [e.g., Anafranil], desipramine [e.g., Pertofrane], doxepin [e.g., Sinequan], imipramine [e.g., Tofranil], nortriptyline [e.g., Aventyl], protriptyline [e.g., Vivactil], trimipramine [e.g., Surmontil]) or
-
- Monoamine oxidase (MAO) inhibitor activity (isocarboxazid [e.g., Marplan], phenelzine [e.g., Nardil], procarbazine [e.g., Matulane], selegi line [e.g., Eldepryl], tranylcypromine [e.g., Parnate])¡X Do not take Zyban while you are taking or within 14 days of taking an MAO inhibitor

Other medical problems
Pregnancy¡XStudies have not been done in pregnant women. However, Zyban has not been reported to cause birth defects or other problems in animal studies.


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